| Interacting proteins: Q9Y6Q9 and Q00403 |
Pubmed |
SVM Score :0.60720985 |
| In vitro binding studies show that F SRC 1 binds to a variety of nuclear hormone receptors in a ligand dependent manner , along with TBP and TFIIB , suggesting that F SRC 1 may play a role as a bridging molecule between nuclear hormone receptors and general transcription factors . 0.60720985^^^ |
|
| Interacting proteins: Q9Y6Q9 and Q00403 |
Pubmed |
SVM Score :0.0 |
| We have analyzed several transcriptional steps that could be involved in the activation : the ability of these receptors 1 ) to interact with several coactivators ( steroid receptor coactivator 1 , SRC 1 ; transcription intermediary factor 1 , TIF 1 ; and estrogen receptor associated protein 140 , ERAP 140 ) and with members of the preinitiation complex [ TATA box binding protein ( TBP ) , transcription factor IIB ( TFIIB ) ] ; 2 ) to exhibit conformational changes revealed by proteolytic digest patterns similar to those observed for the wild type hormone occupied ER ; and 3 ) to bend estrogen response element containing DNA , which is thought to be one of the important phenomena triggering transcriptional activation . ^^^ |
|
| Interacting proteins: Q9Y6Q9 and Q00403 |
Pubmed |
SVM Score :0.0 |
| Chromatin immunoprecipitation analysis showed that E ( 2 ) induced recruitment of C / EBPbeta , ERalpha , SRC 1 , p 300 , pCAF , TFIIB , and Pol 2 , with no change in Sp1 / Sp3 . ^^^ |
|
| Interacting proteins: Q9Y6Q9 and Q00403 |
Pubmed |
SVM Score :0.0 |
| NA |
|