| The human forkhead protein FREAC 2 contains two functionally redundant activation domains and interacts with TBP and TFIIB . ^^^ FREAC 2 was shown to interact in vitro with TBP and TFIIB . ^^^ TFIIB binds FREAC 2 close to the cleft between its two globular domains . ^^^ Overexpression of TFIIB potentiates activation by FREAC 2 in a manner dependent on the FREAC 2 activation domains . ^^^ |