| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.7815785 |
| We show that TFIIB binds to YY 1 , stabilizing its interaction with DNA , and YY 1 contacts the large subunit of polymerase 2 , directing it to the initiation site . 0.7815785^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.57415191 |
| In addition , we find that YY 1 interacts directly with TFIIB , and that one of the two tandemly repeated polypeptide regions of TFIIB spanning the basic domain is responsible for this interaction . 0.57415191^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| TATA binding protein independent initiation : YY 1 , TFIIB , and RNA polymerase 2 direct basal transcription on supercoiled template DNA . ^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| However , protein association studies suggest that c Myc interferes with the ability of YY 1 to contact basal transcription proteins TATA binding protein and TFIIB . . ^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| TBP , TFIIB , TAFII 55 , Sp 1 , and E1A ) has suggested that these interactions are important for determining which particular function of YY 1 is displayed at a specific promoter . ^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| Relief of YY 1 repression was observed in the presence of TFIIB or CBP ( CREB binding protein ) suggesting that YY 1 may exert repression , in part , by sequestering TFIIB / CBP . ^^^ In addition , the N terminal region of CBP that interacts with YY 1 can inhibit YY 1 from binding to TFIIB . ^^^ Thus , CBP may alleviate YY 1 mediated repression , in part , by preventing YY 1 from binding to TFIIB , which is required for VDR mediated transcription . ^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| These studies extend our previous studies related to factors that affect vitamin D receptor ( VDR ) mediated 24 ( OH ) ase transcription ( YY 1 , TFIIB , CBP ) and the effect of signaling pathways on 24 ( OH ) ase transcription and cofactor recruitment . . ^^^ |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P25490 and Q00403 |
Pubmed |
SVM Score :0.0 |
| NA |
|