| Interacting proteins: Q16610 and P98160 |
Pubmed |
SVM Score :0.0 |
| Infection of confluent human umbilical vein endothelial cells by the parasite Trypanosoma cruzi results in the appearance of an altered heparan sulfate proteoglycan ( HSPG ) isolated from the extracellular matrix of infected endothelial cells ( ECMi ) . ^^^ HSPG from ECMi differed from HSPG obtained from the extracellular matrix of uninfected endothelial cells ( ECMu ) by virtue of an 8 10 fold increase in sulfation and a different elution pattern using DEAE Sepharose chromatography . ^^^ In addition , the aFGF binding HSPG isolated from ECMi demonstrated a markedly attenuated synergistic mitogenic activity with aFGF in a cell proliferation assay . ^^^ All of the infection associated changes in HSPG could be demonstrated in HSPG obtained from uninfected endothelial cell cultures grown on ECMi . ^^^ |
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| Interacting proteins: Q16610 and P98160 |
Pubmed |
SVM Score :0.0 |
| Within the dermis , ECM 1 binds to the major heparan sulphate proteoglycan , perlecan . ^^^ |
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| Interacting proteins: Q16610 and P98160 |
Pubmed |
SVM Score :0.0 |
| Perlecan protein core interacts with extracellular matrix protein 1 ( ECM 1 ) , a glycoprotein involved in bone formation and angiogenesis . ^^^ |
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| Interacting proteins: Q16610 and P98160 |
Pubmed |
SVM Score :0.0 |
| NA |
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