| Interacting proteins: P98160 and P54259 |
Pubmed |
SVM Score :0.0 |
| To investigate whether mastoparan and Nod factor activate lipid signalling pathways initiated by phospholipase C ( PLC ) and D ( PLD ) , seedlings were radiolabelled with [ ( 32 ) P ] orthophosphate prior to treatment . ^^^ The roles of PLC and PLD in Nod factor signalling are discussed . . ^^^ |
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| Interacting proteins: P98160 and P54259 |
Pubmed |
SVM Score :0.0 |
| B10 H2b and NOD / LtJ mice manifest many features of primary and secondary Sjgren ' s syndrome ( SjS ) , respectively , an autoimmune disease affecting primarily the salivary and lacrimal glands leading to xerostomia ( dry mouth ) and xerophthalmia ( dry eyes ) . ^^^ A previous study suggested that the T ( H 2 ) cytokine , interleukin ( IL ) 4 , plays an integral role in the development and onset of SjS like disease in the NOD mouse model . ^^^ To define further the role of IL 4 in onset of murine SjS like disease , we have examined two IL 4 gene knockout ( KO ) mouse strains , NOD . ^^^ |
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| Interacting proteins: P98160 and P54259 |
Pubmed |
SVM Score :0.0 |
| In recent years , the NOD mouse has become an accepted model of SjS , exhibiting a spontaneously developing disease that strongly mimics the human condition . ^^^ Two genetic regions , one on chromosome 1 ( designated Aec 2 ) and the second on chromosome 3 ( designated Aec 1 ) of NOD mice , have been shown to be necessary and sufficient to recapitulate SjS like disease in non susceptible C57BL / 6 mice . ^^^ These data suggest SjS like disease in the NOD mouse shows gender specific regulation determined by autosomal genes . . ^^^ |
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