| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.92159747 |
| The results suggest that secreted forms of APP may be involved in stimulating neurite outgrowth from hippocampal neurons and that interactions between APP and HSPG may be important for a neurite outgrowth promoting function . . 0.92159747^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.8393984 |
| HSPG has been shown to bind to A beta , accelerate its fibril formation , and maintain its fibril stability . 0.8393984^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Previous studies have shown the basement membrane form of heparan sulfate proteoglycan ( HSPG ) known as perlecan , co localized to beta amyloid protein ( A beta ) containing amyloid deposits in brains of patients with Alzheimer ' s disease ( AD ) and Down ' s syndrome . ^^^ Although HSPG was localized to diffuse A beta plaques in hippocampus , amygdala , and neocortex , it is not known whether they are present in diffuse A beta plaques in cerebellum . ^^^ In the present study , Alcian blue staining and immunocytochemical techniques were used to determine whether highly sulfated glycosaminoglycans ( GAGs ) and / or HSPG ( perlecan ) were also present in diffuse A beta plaques of cerebellum . ^^^ Even though HSPG immunoreactivity was not present in cerebellar diffuse plaques , all cases ( 4 of 4 ) examined demonstrated HSPG ( both core protein and GAG chain ) immunoreactivity in diffuse A beta plaques in hippocampus . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Heparan sulphate proteoglycan ( HSPG ) core protein and intercellular adhesion molecule 1 ( ICAM 1 ) are absent in the diffuse A beta plaques in the AD cerebellum . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| We demonstrate that heparan sulfate proteoglycan ( HSPG ) and chondroitin sulfate proteoglycan ( CSPG ) inhibit the proteolytic degradation of fibrillar , but not non fibrillar , A beta at physiological pH . ^^^ In accordance with the proteolysis studies , high affinity binding of proteoglycans to fibrillar A beta ( 1 40 ) and A beta ( 1 42 ) is observed from pH 4 to 9 , whereas appreciable binding of HSPG or CSPG to non fibrillar peptide is only seen at pH < 6 . ^^^ Scatchard analysis of fibrillar A beta association with proteoglycans indicates a single affinity interaction , and the binding of both HSPG and CSPG to fibrillar A beta is completely inhibited by free glycosaminoglycan chains . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| The results indicate that the binding of APP to HSPG in the ECM may stimulate the effects of APP on neurite outgrowth . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Our studies suggest that following release from the cell membrane , APP interacts with components of the extracellular matrix ( ECM ) such as the heparan sulfate proteoglycans ( HSPG ' s ) . ^^^ The interaction of APP with HSPG ' s may be important for the function of APP . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| One hundred percent of animals receiving infusions of synthetic beta amyloid protein ( A beta 1 40 ) plus a specific heparan sulfate proteoglycan ( HSPG ) for 1 week or 7 weeks ( following 2 week infusions ) demonstrated Congo red and thioflavin S positive deposits adjacent to the infusion site . ^^^ Significant increases in Congo red staining were observed in animals infused with A beta plus HSPG versus those infused with only A beta . ^^^ By 7 weeks , only animals infused with A beta plus HSPG demonstrated compaction of the Congo red material from amorphous , wispy deposits ( at 1 week ) to stellate deposits resembling a Maltese cross . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Cultures of normal human synovial cells were shown to contain the large 14 . 5 kb perlecan mRNA and produced substantial amounts of perlecan core protein as shown by immunohistochemistry employing specific human perlecan Ab . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Co infusion of the specific heparan sulfate proteoglycan ( HSPG ) , perlecan , and beta amyloid protein ( A beta ) into rodent hippocampus leads to a consistent animal model to study the effects of fibrillar A beta amyloid in brain [ Snow , A . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| In holding zinc inside plaques , HSPG may contribute in addition to Abeta . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| HDL , ApoE and HSPG , may be involved in the regulation of reverse cholesterol transport in the brain and in the processing of Abeta . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| HSPG is produced by SMCs and promotes A beta fibrillogenesis . ^^^ We propose a pathogenetic model of CAA , in which the ApoE and HSPG mediated clearance of CSF derived A beta peptides by SMCs protects the vascular extracellular matrix against critical A beta concentrations . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| In the case of Alzheimer ' s disease ( AD ) , HSPG , such as perlecan , co accumulates with amyloid beta protein ( Abeta ) , a main constituent of amyloid plaques , and paired helical filaments ( PHFs ) . ^^^ Additionally , in vitro , HSPG accelerates both Abeta fibril and PHF formation and protects Abeta from degradation . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Immunocytochemistry has demonstrated that even with this rapid progression , Abeta deposits within the neuropil and cerebrovascular system all co localize with heparan sulfate proteoglycans ( HSPG ) . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| However , the expression of HSPG was lowered in AAA and was significantly negatively correlated with the expression of heparanase and microvessel density . ^^^ Both of heparanase and HSPG were mainly located in adventitia and intima of AAA walls . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Glypican 1 as an Abeta binding HSPG in the human brain : its localization in DIG domains and possible roles in the pathogenesis of Alzheimer ' s disease . ^^^ Further analysis revealed that glypican 1 is the major HSPG localized in detergent insoluble glycosphingolipid enriched ( DIG ) domains where all machineries for Abeta production exist and Abeta is accumulated as monomeric and oligomeric forms . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND : A common feature of Alzheimer ' s disease ( AD ) pathology is the abundance of activated microglia in neuritic plaques containing amyloid beta protein ( Abeta ) and associated molecules including heparan sulfate proteoglycan ( HSPG ) . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Abeta that was fluorescently labelled at the N terminus ( fluo Abeta ) bound to Matrigel as well as to the basement membrane heparan sulfate proteoglycan ( HSPG ) perlecan and laminin . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Previous studies have demonstrated the immunolocalization of perlecan , a specific heparan sulfate proteoglycan , to the beta amyloid protein ( A beta ) containing amyloid deposits within the walls of blood vessels ( i . e . , congophilic angiopathy ) in Alzheimer ' s disease ( AD ) brain . ^^^ In the present investigation , the differential binding of previously characterized endothelial cell ( EC ) and smooth muscle cell ( SMC ) derived PGs to A beta was examined to determine whether the accumulation of A beta in cerebrovascular amyloid deposits may be due to its interactions with perlecan . ^^^ Pretreatment of AA amyloidotic splenic and liver tissue sections with synthetic A beta ( 1 28 ) produced strong immunoreactivity with A beta antibodies at tissue sites enriched in perlecan which was partially removed by pretreatment with heparitinase , but not by chondroitin ABC lyase . [ 35S ] Sulfate labeled proteoglycans ( PGs ) derived from cultured ECs and SMCs bound to affinity columns containing A beta ( 1 28 ) or ( 1 40 ) , with virtually no binding to A beta ( 40 1 ) ( reverse peptide ) , beta amyloid precursor protein ( 410 429 ) , or bovine serum albumin . ^^^ Characterization of EC and SMC PGs bound to A beta ( 1 28 ) revealed strong binding by perlecan , weak binding by decorin and biglycan , two dermatan sulfate proteoglycans , and lack of binding by versican / PG M , a large chondroitin sulfate proteoglycan . ^^^ Binding of 125I labeled perlecan to A beta ( 1 28 ) was strongly inhibited by isolated perlecan and to a lesser extent by heparin , but not by chondroitin 6 sulfate or unsulfated dextran sulfate . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Our previous studies have implicated perlecan , a specific heparan sulfate proteoglycan , in the pathogenesis of fibrillar beta amyloid protein ( A beta ) accumulation and persistence in Alzheimer ' s disease ( AD ) brain . ^^^ In the present investigation , we determined if perlecan mRNA was present in rodent and human brain tissue and whether perlecan persistence in A beta amyloid deposits in AD hippocampus may be partly due to increased perlecan expression and / or decreased perlecan degradation . ^^^ These results therefore suggest that perlecan persistence in A beta amyloid deposits in late stage AD may be primarily due to decreased perlecan degradation and removal . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| The origin of the heparan sulfate proteoglycan ( PG ) , perlecan , in beta amyloid protein ( A beta ) containing amyloid deposits in Alzheimer ' s disease ( AD ) brain is not known . ^^^ Following a 1 week continuous infusion of A beta ( 1 40 ) into rodent hippocampus , immunoperoxidase immunocytochemistry and double labeled immunofluorescent studies revealed perlecan accumulation primarily localized to microglia / macrophages within the A beta infusion site . ^^^ These studies have identified microglia / macrophages as one potential source of perlecan ( or a perlecan related macromolecule ) which may be important for the ongoing accumulation of both perlecan and A beta in the amyloid deposits of AD . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Perlecan binds to the beta amyloid proteins ( A beta ) of Alzheimer ' s disease , accelerates A beta fibril formation , and maintains A beta fibril stability . ^^^ Perlecan is a specific heparan sulfate proteoglycan that accumulates in the fibrillar beta amyloid ( A beta ) deposits of Alzheimer ' s disease . ^^^ Perlecan purified from the Engelbreth Holm Swarm tumor was used to define perlecan ' s interactions with A beta and its effects on A beta fibril formation . ^^^ Using a solid phase binding immunoassay , freshly solubilized full length A beta peptides bound immobilized perlecan at two sites , representing both high affinity [ K ( D ) = approximately 5 . 8 10 10 ( 11 ) M for A beta ( 1 40 ) ; K ( D ) = approximately 6 . 5 10 10 ( 12 ) M for A beta ( 1 42 ) ] and lower affinity [ K ( D ) = 3 . 5 10 10 ( 8 ) M for A beta ( 1 40 ) ; K ( D ) = 4 . 3 10 10 ( 8 ) M for A beta ( 1 42 ) ] interactions . ^^^ An increase in the binding capacity of A beta ( 1 40 ) to perlecan correlated with an increase in A beta amyloid fibril formation during a 1 week incubation period . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Versican , perlecan , and biglycan levels were significantly elevated in AAA smooth muscle cell cultures . ^^^ Elevated levels of intact and processed perlecan core protein were identified in AAA cultures by means of immunoblotting with a monoclonal antibody to perlecan core protein ( A 76 ) . ^^^ ELISA measurements confirmed that perlecan levels were significantly higher in AAA smooth muscle cell cultures compared with the normal arterial tissue and tissue affected by atherosclerotic occlusive disease . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Our previous studies have demonstrated that perlecan and perlecan derived glycosaminoglycans ( GAGs ) not only bind beta amyloid protein ( Abeta ) 1 40 and 1 42 , but are also potent enhancers of Abeta fibril formation and stabilize amyloid fibrils once formed . ^^^ However , it was not determined which moieties in perlecan heparan sulfate GAG chains may be responsible for the observed effects and whether other GAGs were also capable of a similar enhancement of Abeta fibril formation as observed with perlecan GAGs . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| A beta and perlecan in rat brain : glial activation , gradual clearance and limited neurotoxicity . ^^^ A beta 1 40 and perlecan ( A beta + perlecan ) were infused into rat hippocampus for 1 week via osmotic pumps . ^^^ The neuron free area resulting from A beta + perlecan was significantly larger than that found after infusions of A beta 40 1 and perlecan ( reverse A beta + perlecan ) , perlecan alone or phosphate buffered saline vehicle . ^^^ Following infusion of A beta + perlecan , the glial cells segregated in a manner similar to that associated with compacted amyloid plaques in Alzheimer ' s disease ( AD ) . ^^^ Intact , apparently healthy neurons were found immediately adjacent to the A beta + perlecan deposit . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| In the present study , the basement membrane protein laminin was found to bind Abeta 1 40 with a single dissociation constant , K ( d ) = 2 . 7 10 10 ( 9 ) M , and serve as a potent inhibitor of Abeta fibril formation . 25 microM of Abeta 1 40 was incubated at 37 degrees C for 1 week in the presence of 100 nM of laminin or other basement membrane components , including perlecan , type 4 collagen , and fibronectin to determine their effects on Abeta fibril formation as evaluated by thioflavin T fluorometry . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| METHODS : Serial cryosections of post mortem eyes of 22 subjects with DM and 7 controls were stained with antibodies against the core proteins of the basement membrane HSPGs agrin ( Abs Bl 31 and JM 72 ) and perlecan ( Ab 1948 ) , and four antibodies against heparan sulfate side chains ( HS ) ( Abs JM 403 , HepSS 1 , JM 13 , 3G10 ) . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Addition of fetal calf serum or human AB serum impaired PLC induced cytotoxicity . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| CD 3 stimulation of T cells induces tyrosine phosphorylation of PLC gamma 1 and causes 8 10 fold higher yield of PLC activity with anti phosphotyrosine antibody ( APTyr Ab ) from activated cells than from non activated cells . ^^^ Genistein , an inhibitor of protein tyrosine kinase , decreases this yield of AP Tyr Ab bound PLC activity from activated cells and lowers the level of Ca2+ mobilization . ^^^ Furthermore , phorbol ester and forskolin treatment of cells before CD 3 stimulation reduces the level of tyrosine phosphorylation of PLC gamma 1 and the PLC activity associated with APTyr Ab . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Peptide specific antiserum ( Ab 1109 ) directed against a highly conserved sequence of the Y region found in several PLC isozymes was used to detect any PLC belonging to this family . ^^^ In resealed ROS and washed ROS membranes , Ab 1109 recognized an additional protein of apparent molecular mass of 70 kDa not usually detectable in soluble extracts of ROS , suggesting the presence of at least two isozymes of PLC in ROS . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| The results showed that in PLC patients , plasma total amino acid ( TAA ) , branched chain amino acid ( BCAA ) , glycogenic amino acid , glutamine , histidine and arginine were lowered , while plasma aromatic amino acid ( AAA ) and methionine did not decrease significantly resulting in the BCAA / AAA ratio decline . ^^^ Comparing 8 / 22 subclinical and 14 / 22 clinical liver cancers with healthy controls respectively , it was found that there was a decrease of plasma TAA , glutamine , arginine , histidine , BCAA and BCAA / AAA ratio , and an increase of tyrosine , in subclinical stage of PLC . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| A number of cellular proteins , including PLC gamma 2 , but not PLC delta 1 , were phosphorylated on a tyrosine residue by the stimulation of either PDGF BB or AB . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| PDGF receptors are coupled to multiple signaling pathways , among them phospholipase C gamma PDGF BB rapidly phoshorylated PLC gamma , while phosphorylation by PDGF AB was barely detectable . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Anti PLC gamma 2 Ab seemed to recognize the same protein as the tyrosine phosphorylated 140 kDa protein . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| A neurotoxic fragment of amyloid , Abeta 25 35 , incubated in the presence of endogenous Ca2+ , increased significantly the PI PLC activity of normoxic brain . ^^^ In its non aggregated form , Abeta 25 35 activates PI PLC but in the aggregated form the enzymatic activity decreased . ^^^ Thus , Abeta 25 35 exerts a similar effect on the membrane bound PI PLC from normoxic brain or subjected to ischemia reperfusion injury . ^^^ Ischemia reperfusion injury had no effect on Abeta evoked alterations of synaptic plasma membrane bound PI PLC . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Fresh water soluble A beta 25 35 activated PI PLC in SPM markedly by two to threefold , but this effect was absent in the presence of 2 mM CaCl 2 . ^^^ Moreover , A beta 25 35 had no effect on basal PIP 2 PLC activity and cytosolic PI PLC and PIP 2 PLC . ^^^ The aggregated form of A beta 25 35 significantly inhibited PIP 2 PLC only in the presence of endogenous CaCl 2 . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| We evaluated the role of protein kinases , calcium and phospholipase C ( PLC ) in modulating APP mRNA levels . ^^^ However the protein kinase C ( PKC ) , protein kinase A ( PKA ) or PLC pathways did not mediate these changes in APP mRNA levels . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Our previous studies indicated that Alzheimer ' s disease ( AD ) related amyloid beta peptide ( Abeta ) significantly altered muscarinic cholinergic receptor ( mChR ) signaling on the level of G protein regulated phospholipase C ( PLC ) leading to the lower formation of inositol 1 , 4 , 5 triphosphate ( IP 3 ) and diacylglycerol ( DAG ) . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Neuroprotective effect of FBP 3 . 5 mM against Abeta induced neurotoxicity in hippocampal slices was attenuated by addition of phospholipase C ( PLC ) inhibitor , U 73122 , mitogen activated extracellular signal protein kinase ( MEK ) inhibitor , U 0126 , or extracellular signal activated protein kinase ( ERK ) inhibitor , PD 98059 at 24 h , 48 h and 72 h . ^^^ Our results suggested FBP has neuroprotective effect against Abeta induced neurotoxicity in hippocampal slice cultures , and FBP plays role not only as an alternative energy source , but also a modulator of PLC and MEK / ERK pathways to regulate the cellular response and survival . . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Helix asparsa agglutinin ( HAA ) , Helix pomatia agglutinin ( HPA ) and monoclonal anti A antibody recognized A antigens in the mucous cells of salivary glands from blood group A or AB nonsecretor as well as secretor individuals , whereas Dolichos biflorus agglutinin ( DBA ) , Griffonia simplicifolia agglutinin 1 ( GSA 1 ) , Sophora japonica agglutinin ( SJA ) and Vicia villosa agglutinin ( VVA ) did not bind to them from nonsecretors . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| The blood group B reactive lectins , specific for alpha D galactose ( alpha Gal ) or GalNAc , respectively , GSA 1 B 4 and Sophora japonica agglutinin ( SJA ) , bound to the endothelia in specimens from blood group B or AB and in other specimens bound only to certain tubules . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| SJA , on the other hand , bound to suprabasal epithelial cells and to endothelial cells in specimens from blood group B , AB and A individuals . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| Sophora japonica agglutinin ( SJA ) , a blood group B reactive lectin , labeled vascular endothelial cells in tissues from blood group A , AB , and B donors . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| HTT ( anti A beta sE beta sJs ) serum absorbed with B10 . ^^^ |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P98160 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|