| Interacting proteins: P28715 and P78549 |
Pubmed |
SVM Score :0.0 |
| No induction at the transcriptional level of any of the base excision repair genes , NTH 1 ( NTHL 1 ) , OGG 1 , NEIL 1 , NEIL 2 , NEIL 3 , APE 1 , POLB , or accessory protein genes , LIG 3 , XRCC 1 or XPG , was found at gamma radiation doses ranging from 1 cGy to 2 Gy in a 24 h period . ^^^ |
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| Interacting proteins: P28715 and P78549 |
Pubmed |
SVM Score :0.0 |
| We have searched for the factors interacting with NTH 1 by using a pull down assay and found that GST NTH 1 fusion protein precipitates proliferating cell nuclear antigen ( PCNA ) and p 53 as well as XPG from human cell free extracts . ^^^ GST NTH 1 also bound to recombinant FLAG tagged XPG , PCNA , and ( His ) 6 tagged p 53 proteins , indicating direct protein protein interaction between those proteins . ^^^ Furthermore , His p 53 and FLAG XPG , but not PCNA , stimulated the Tg DNA glycosylase / AP lyase activity of GST NTH 1 or NTH 1 . ^^^ |
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| Interacting proteins: P28715 and P78549 |
Pubmed |
SVM Score :0.0 |
| The commonly up regulated genes were OGG 1 and NTH 1 of base excision repair ; ERCC 5 , RAD23A , and RAD23B of nucleotide excision repair ; and RAD 50 , RAD 52 , and RAD 54 involved in DNA strand break repair . ^^^ |
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