| Interacting proteins: P78545 and P00533 |
Pubmed |
SVM Score :0.0 |
| Expression of ELF 3 , EphB 4 , EpCAM , EGFR , CEA and MGB 1 was found to be both specific for the tumor cell , as demonstrated by the absence of a signal in most 100 cell PBMNC controls , and sensitive enough to detect a single tumor cell in 100 PBMNCs using a single round of RT PCR . ^^^ CONCLUSIONS : ELF 3 , EphB 4 , EpCAM , EGFR , CEA and MGB 1 are appropriate RT PCR markers for use in a marker panel to detect disseminated breast cancer cells after immunomagnetic enrichment . . ^^^ |
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| Interacting proteins: P78545 and P00533 |
Pubmed |
SVM Score :0.0 |
| A growth factor stimulated ( MAP 2 related ) protein kinase , ERT , that phosphorylates the epidermal growth factor receptor at Thr 669 has been purified from KB human tumor cells by Northwood and co workers ( Northwood , 1 . ^^^ |
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| Interacting proteins: P78545 and P00533 |
Pubmed |
SVM Score :0.0 |
| ErbB 2 activation of ESX gene expression . ^^^ Transient reporter assays using the ESX promoter show that ESX transcription is regulated by ErbB receptor signalling . ^^^ In cell lines and in 45 primary ductal breast cancers we show that ESX transcript expression significantly correlates with ErbB 2 transcript levels . ^^^ Moreover , expression of ErbB 2 in cells upregulates ESX promoter activity while inhibition of ErbB 2 or its downstream signaling pathways decrease both ESX promoter activity and endogenous ESX protein levels . ^^^ These results indicate that the ESX promoter represents a transcriptional target of ErbB 2 , and ESX expression may represent a downstream mediator of ErbB 2 signaling and ErbB 2 induced gene expression . . ^^^ |
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| Interacting proteins: P78545 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P78545 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P78545 and P00533 |
Pubmed |
SVM Score :0.0 |
| NA |
|