Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P78509 and Q9UN74 Pubmed SVM Score :0.0
CNRc 1 and c 2 lack the Arg Gly Asp ( RGD ) sequence that is conserved in the EC 1 of CNR 1 8 , which is necessary for binding to Reelin . ^^^
Interacting proteins: P78509 and Q9UN74 Pubmed SVM Score :0.0
Here we show the following : ( 1 ) the central fragment is necessary and sufficient for receptor binding in vitro and for Dab 1 phosphorylation in neuronal cultures ; ( 2 ) Reelin does not bind the protocadherin cadherin related neuronal receptor ( CNR 1 ) as reported previously ; ( 3 ) Reelin and its central fragment are equally able to rescue the reeler phenotype in a slice culture assay ; and ( 4 ) anti receptor antibodies can induce Dab 1 phosphorylation but do not correct the reeler phenotype in slices . ^^^ These observations show that the function of Reelin is critically dependent on the central fragment generated by processing but primarily independent of interactions with CNR 1 and on the N terminal region . ^^^
Interacting proteins: P78509 and Q9UN74 Pubmed SVM Score :0.0
The analysis showed that more than 50 % of these genes , particularly AKT 1 , BDNF , CAPON , CCKAR , CHRNA 7 , CNR 1 , COMT , DNTBP 1 , GAD 1 , GRM 3 , IL 10 , MLC 1 , NOTCH 4 , NRG 1 , NR4A2 / NURR1 , PRODH , RELN , RGS 4 , RTN4 / NOGO and TNF , are subject to regulation by hypoxia and / or are expressed in the vasculature . ^^^