| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| In short term neocortical cultures , concentrations of epidermal growth factor and amphiregulin ( 2 9 pM ) decreased the expression of glutamate receptor interacting protein 1 ( GRIP 1 ) and synapse associated protein 97 kDa ( SAP 97 ) without affecting postsynaptic density 95 ( PSD 95 ) levels and glial proliferation . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NMDA receptors have been found to bind to the PSD 95 family of proteins , whereas AMPA receptors interact with the PDZ domain containing protein GRIP ( glutamate receptor interacting protein ) . ^^^ PSD 95 and GRIP contain multiple PDZ domains as well as other protein protein interaction motifs that help to form large macromolecular complexes that may be important for the formation and plasticity of synapses . . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| We show that the protein interactions of the ABP / GRIP family differ from the PSD 95 family , which binds N methyl D aspartate ( NMDA ) receptors . ^^^ ABP and GRIP also form homo and heteromultimers through PDZ PDZ interactions but do not bind PSD 95 . ^^^ We suggest that the ABP / GRIP and PSD 95 families form distinct scaffolds that anchor , respectively , AMPA and NMDA receptors . . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| Biochemical studies reveal that GRIP is largely membrane associated and enriched in the postsynaptic density ( PSD ) , though not as highly concentrated in the PSD as is PSD 95 . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NMDA receptor NR 2 subunits bind to the PSD 95 family of proteins , whereas AMPA receptor subunits GluR2 / 3 bind to GRIP . ^^^ By virtue of their multiple protein binding domains ( e . g . , three PDZs in PSD 95 and seven PDZs in GRIP ) , PSD 95 and GRIP can function as multivalent proteins that organize a specific cytoskeletal and signaling complex associated with each class of glutamate receptor . ^^^ |
|
| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| We suggest that the ABP / GRIP and PSD 95 families form distinct scaffolds that anchor , respectively , AMPA and NMDA receptors . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| The PDZ domain containing proteins , such as PSD 95 and GRIP , have been suggested to be involved in the targeting of glutamate receptors , a process that plays a critical role in the efficiency of synaptic transmission and plasticity . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| The multiple PSD 95 , Dlg , and Zo 1 ( PDZ ) domain protein , glutamate receptor interacting protein ( GRIP ) , is involved in the clustering and trafficking of the alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate receptor by directly binding to the cytoplasmic tail of the receptor ' s GluR 2 subunit . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| We also studied the synaptic localization of the two postsynaptic density proteins PSD 95 and glutamate receptor interacting protein ( GRIP ) . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| When coexpressed in human embryonic kidney 293 cells , PrRP receptor was able to coimmunoprecipitate the three PDZ domain proteins known to interact with AMPA receptors : glutamate receptor interacting protein ( GRIP ) , AMPA binding protein ( ABP ) , and protein that interacts with C kinase ( PICK 1 ) , but not the PDZ domain protein PSD 95 , which does not interact with AMPA receptors . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| We identified four PDZ domain containing proteins , syntenin , PICK 1 , GRIP , and PSD 95 , as interactors with the kainate receptor ( KAR ) subunits GluR 5 ( 2b , ) GluR 5 ( 2c ) , and GluR 6 . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| We have found that DR reduced the expression of the NMDA receptor 2A subunit and its associated protein PSD 95 ( postsynaptic density 95 ) , of GRIP ( AMPA glutamate receptor interacting protein ) , and of the biosynthetic enzyme GAD ( glutamic acid decarboxylase ) . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| Pull down assay showed that r p 55 protein interacted with r p 55 itself and various PSD proteins , such as PSD 95 , SAP 97 , GKAP , CASK , GRIP , neuroligin , cadherin , tubulin , actin , alpha internexin , neurofilament L and Ca ( 2+ ) / calmodulin dependent protein kinase 2 , through its PDZ , SH 3 , HOOK or GK domains . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| Exercise increased the immunocontent of GluR 1 ( 129 % ) , SAP 97 ( 179 % ) , GRIP 1 ( 129 % ) , and in less extent , GluR2 / 3 ( 118 % ) and PSD 95 ( 112 % ) proteins . ^^^ |
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| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y3R0 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
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