| Interacting proteins: Q9Y2T3 and P78352 |
Pubmed |
SVM Score :0.0 |
| Cypin : a cytosolic regulator of PSD 95 postsynaptic targeting . ^^^ Affinity chromatography identifies cypin as a major PSD 95 binding protein in brain extracts . ^^^ Overexpression of cypin in hippocampal neurons specifically perturbs postsynaptic trafficking of PSD 95 and SAP 102 , an effect not produced by overexpression of other PDZ ligands . ^^^ |
|
| Interacting proteins: Q9Y2T3 and P78352 |
Pubmed |
SVM Score :0.0 |
| Exocyst complex subunit sec 8 binds to postsynaptic density protein 95 ( PSD 95 ) : a novel interaction regulated by cypin ( cytosolic PSD 95 interactor ) . ^^^ |
|
| Interacting proteins: Q9Y2T3 and P78352 |
Pubmed |
SVM Score :0.0 |
| Our laboratory previously cloned and characterized cypin , a protein that decreases PSD 95 family member localization and regulates dendrite number . ^^^ Cypin contains zinc binding , collapsin response mediator protein ( CRMP ) homology , and PSD 95 , Discs large , zona occludens 1 binding domains . ^^^ |
|
| Interacting proteins: Q9Y2T3 and P78352 |
Pubmed |
SVM Score :0.0 |
| The effect of PSD 95 is activity independent and is antagonized by cypin , a nonsynaptic protein that regulates PSD 95 localization . ^^^ Binding of cypin to PSD 95 correlates with formation of stable dendrite branches . ^^^ |
|
| Interacting proteins: Q9Y2T3 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
|