| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.83996423 |
| Using coimmunoprecipitation assays , we confirmed the direct interactions between ErbB 4 and PSD 95 in transfected heterologous cells , as well as in vivo , where both proteins are coimmunoprecipitated from brain lysates . 0.83996423^^^ |
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| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.77654129 |
| ErbB 4 associates with the PSD 95 ( also known as SAP 90 ) family members including PSD 95 , SAP 97 , and SAP 102 whereas ErbB 2 interacts with Erbin and PICK 1 . 0.77654129^^^ |
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| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.0 |
| Regulation of neuregulin signaling by PSD 95 interacting with ErbB 4 at CNS synapses . ^^^ We report that ErbB 4 is enriched in the postsynaptic density ( PSD ) and associates with PSD 95 . ^^^ Heterologous expression of PSD 95 enhanced NRG activation of ErbB 4 and MAP kinase . ^^^ PSD 95 formed a ternary complex with two molecules of ErbB 4 , suggesting that PSD 95 facilitates ErbB 4 dimerization . ^^^ |
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| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.0 |
| Our recent studies indicate that ErbB 4 interacts with postsynaptic density ( PSD ) 95 ( SAP 90 ) , a PDZ domain containing protein that does not interact with ErbB 2 or ErbB 3 . ^^^ |
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| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.0 |
| In transfected human embryonic kidney 293 cells , the partitioning of ErbB 4 into a detergent insoluble fraction that includes lipid rafts was increased by PSD 95 ( postsynaptic density 95 ) , through interaction of the ErbB 4 C terminus with the PDZ [ PSD 95 / Discs large / zona occludens 1 ] domains of PSD 95 . ^^^ |
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| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.0 |
| To evaluate possible causes for this hyperactivation of erbB 4 signaling , we examined the association of erbB 4 with PSD 95 ( postsynaptic density protein of 95 kDa ) , as this association has been shown to facilitate activation of erbB 4 . ^^^ Schizophrenia subjects showed substantial increases in erbB 4 PSD 95 interactions . ^^^ |
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| Interacting proteins: Q15303 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
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