| Interacting proteins: O14936 and P78352 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: O14936 and P78352 |
Pubmed |
SVM Score :0.0 |
| Intracellularly , the neurexin / neuroligin junction is bound by CASK on the neurexin side and PSD 95 on the neuroligin side . ^^^ CASK and PSD 95 are homologous membrane associated guanylate kinases that bind to the neurexin / neuroligin junction via PDZ domains , creating an asymmetric junction ( neurexin / neuroligin ) with similar intracellular binding partners . ^^^ |
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| Interacting proteins: O14936 and P78352 |
Pubmed |
SVM Score :0.0 |
| CASK , an adaptor protein of the plasma membrane , is composed of an N terminal calcium / calmodulin dependent protein ( CaM ) kinase domain , central PSD 95 , Dlg , and ZO 1 / 2 domain ( PDZ ) and Src homology 3 ( SH 3 ) domains , and a C terminal guanylate kinase sequence . ^^^ |
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| Interacting proteins: O14936 and P78352 |
Pubmed |
SVM Score :0.0 |
| Surprisingly , and in contrast to previously published studies , we failed to detect GMP binding to the MAGUKs postsynaptic density 95 ( PSD 95 ) and CASK . ^^^ |
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| Interacting proteins: O14936 and P78352 |
Pubmed |
SVM Score :0.0 |
| Pull down assay showed that r p 55 protein interacted with r p 55 itself and various PSD proteins , such as PSD 95 , SAP 97 , GKAP , CASK , GRIP , neuroligin , cadherin , tubulin , actin , alpha internexin , neurofilament L and Ca ( 2+ ) / calmodulin dependent protein kinase 2 , through its PDZ , SH 3 , HOOK or GK domains . ^^^ |
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| Interacting proteins: O14936 and P78352 |
Pubmed |
SVM Score :0.0 |
| Similarly , mutation of lin 2 , a related MAGUK in Caenorhabditis elegans , blocks vulval development , and mutation of the postsynaptic density protein PSD 95 impairs synaptic plasticity in mammalian brain . ^^^ |
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