| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| Peptide fragments derived from purified p 30 and p 38 facilitated the molecular cloning and sequencing of cDNAs coding for these two polypeptides , which are now designated as Rpp 30 and Rpp 38 , respectively . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| Two of these proteins , Rpp 30 and Rpp 38 , are Th autoantigens . ^^^ Recombinant Rpp 30 and Rpp 38 are also recognized by Th sera from systemic sclerosis patients . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| In HeLa cells , the tRNA processing enzyme ribonuclease P ( RNase P ) consists of an RNA molecule associated with at least eight protein subunits , hPop 1 , Rpp 14 , Rpp 20 , Rpp 25 , Rpp 29 , Rpp 30 , Rpp 38 , and Rpp 40 . ^^^ Five of these proteins ( hPop1p , Rpp 20 , Rpp 30 , Rpp 38 , and Rpp 40 ) have been partially characterized . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| In addition , we show that the human RNase P proteins Rpp 30 and Rpp 38 are also associated with the RNase MRP complex . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| Subunits hpop 1 , Rpp 21 , Rpp 29 , Rpp 30 , Rpp 38 , and Rpp 40 are involved in extensive , but weak , protein protein interactions in the holoenzyme complex . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| The genetic analysis indicates that subunits Rpp 21 , Rpp 29 , Rpp 30 , and Rpp 38 interact directly with H 1 RNA . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| The reactivity to RNase P subunits was examined by immunoprecipitating ( 35 ) S labelled recombinant Rpp 38 , Rpp 30 , and hPop 1 produced by in vitro transcription and translation . ^^^ Similar percentages of patients with and without SSc showed immunoreactivity to Rpp 38 and Rpp 30 , but more patients with SSc than patients without SSc showed a reactivity to hPop 1 ( 93 % 5 14 % ; p=0 . 002 ) . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| Up to now , 10 protein subunits of these complexes have been described , designated hPop 1 , hPop 4 , hPop 5 , Rpp 14 , Rpp 20 , Rpp 21 , Rpp 25 , Rpp 30 , Rpp 38 and Rpp 40 . ^^^ |
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| Interacting proteins: P78345 and P78346 |
Pubmed |
SVM Score :0.0 |
| The analysis of individual protein subunits revealed that hPop 4 ( also known as Rpp 29 ) , Rpp 21 , Rpp 20 , and Rpp 25 only sedimented in 12S fractions , whereas hPop 1 , Rpp 40 , Rpp 38 , and Rpp 30 were also found in 60 80S fractions . ^^^ Furthermore , Rpp 20 and Rpp 25 appear to be associated with only a subset of RNase MRP particles , in contrast to hPop 1 , Rpp 40 , Rpp 38 , and Rpp 30 ( and possibly also hPop 5 ) , which are probably associated with all RNase MRP complexes . ^^^ |
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