Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P78314 and P43403 Pubmed SVM Score :0.0
In addition to Zap 70 , the 3BP2 SH 2 domain associated in vitro with LAT , Grb 2 , PLCgamma 1 , and Cbl from activated T cell lysates . ^^^ Thus , 3BP2 is an important adaptor that may couple activated Zap 70 / Syk to a LAT containing signaling complex involved in TCR mediated gene transcription . . ^^^
Interacting proteins: P78314 and P43403 Pubmed SVM Score :0.0
Furthermore , point mutation of Arg ( 486 ) in the 3BP2 SH 2 domain that couples ZAP 70 to LAT dramatically reduces NFAT activation . ^^^