| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.77652397 |
| SGT 1 associates with SKP 1 and CUL 1 , subunits of the SCF ( Skp 1 Cullin F box ) ubiquitin ligase complex . 0.77652397^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| A series of protein interactions were identified in which Siah is physically linked to Ebi by association with a novel Sgt 1 homolog SIP that binds Skp 1 , a central component of Skp 1 Cullin F box complexes . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| A recently discovered yeast homolog of CacyBP / SIP , Sgt 1 , associates with Skp 1 and regulates its function in the Skp1 / Cullin1 / F box complex ubiquitin ligase and in kinetochore complexes . ^^^ Moreover , S100A6 does not influence Skp 1 Sgt1 binding , a result suggesting that separate Sgt 1 domains are responsible for interactions with S100A6 and Skp 1 . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| We identified a novel splice variant of human SGT 1 ( SUGT 1 ) , a suppressor of the G 2 allele of SKP 1 , by analysis of 8 human EST clones whose open reading frame encoded 365 amino acids . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| These interactions occur both dependent and independent of Rar 1 ( required for Mla 12 resistance ) and Sgt 1 ( Suppressor of G two allele of skp 1 ) , which are differentially required for diverse plant disease resistance pathways . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| In budding yeast , Sgt 1 , together with Skp 1 , is required for assembly of the core kinetochore complex ( CBF 3 ) via Ctf 13 activation . ^^^ We also have determined that Skp 1 and Hsc 82 ( a yeast Hsp 90 protein ) bind to the N terminal region of Sgt 1 that contains tetratricopeptide repeat motifs . ^^^ Results of sequence and phenotypic analyses of sgt 1 mutants strongly suggest that the N terminal region containing the Hsc 82 binding and Skp 1 binding domains of Sgt 1 is important for the kinetochore function of Sgt 1 . ^^^ We found that Hsp 90 ' s binding to Sgt 1 stimulates the binding of Sgt 1 to Skp 1 and that Sgt 1 and Hsp 90 stimulate the binding of Skp 1 to Ctf 13 , the F box core kinetochore protein . ^^^ Our results strongly suggest that Sgt 1 and Hsp 90 function in assembling CBF 3 by activating Skp 1 and Ctf13 . . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| This cDNA is 1404 bp and contains an open reading frame from 68 to 1165 encoding a putative protein of 365 amino acids ( SGT1 . 2 ) that share 90 % identities to Homo sapiens SGT 1 , suppressor of G 2 allele of SKP 1 at protein level . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| Through interacting with suppressor of the G 2 allele of Skp 1 ( SGT 1 ) and Hsp 90 , plant CHORD containing protein RAR 1 ( required for Mla resistance 1 ) plays a critical role in disease resistance mediated by multiple R genes . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| SGT1B [ suppressor of G 2 allele of SKP 1 ( SGT 1 ) , suppressor of kinetochore protein ( SKP 1 ) ] was identified as the antigen recognized by CTL G3b . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| We have previously shown that SKP 1 and SGT 1 balance the assembly and turnover of CBF 3 complexes , a cycle that we suggest is independent of its role in chromosome segregation ( Rodrigo Brenni , M . ^^^ |
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| Interacting proteins: Q9Y2Z0 and P63208 |
Pubmed |
SVM Score :0.0 |
| We found that HSP 90 associates with SGT 1 ( suppressor of G 2 allele of skp 1 ; SUGT 1 ) in human cells and that depletion of SGT 1 sensitizes HeLa cells to 17 AAG . ^^^ |
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