| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.94692431 |
| As in Shc , N Shc can bind activated EGF receptor , become tyrosine phosphorylated , and form a complex with Grb 2 adapter protein following EGF stimulation . 0.94692431^^^ |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| Expression of Shc family protein ( Shc / ShcA , SCK / ShcB and N Shc / ShcC ) and Grb 2 mRNAs in the hypoglossal motoneurons after axotomy was examined by in situ hybridization . ^^^ |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| We found that RSK 1 , Sos 1 , N Shc 66 kDa , N Shc 52 kDa , and Grb 2 were present in the PSD fraction , and cPLA ( 2 ) was present in the synaptic plasma membrane fraction . ^^^ |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| The ShcC protein is predicted to have a C terminal SH 2 domain , a CH 1 region with a putative Grb 2 binding site , and an N terminal PTB domain . ^^^ |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| Immunoprecipitation followed by Western analysis demonstrated that activated TrkB , composed of the intracellular domain of TrkB fused to glutathione S transferase ( GST TrkB ( ICD ) ) , promoted the association of ShcC and Grb 2 in yeast . ^^^ Yeast cells transformed with both Myr ShcC and hSOS Grb 2 ( referred to as scheme 1 ) or Myr Grb 2 and hSOS ShcC ( scheme 2 ) did not grow at non permissive temperature ; the additional transformation of GST TrkB ( ICD ) enabled growth . ^^^ |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92529 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|