| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| One of the mechanisms of TCR mediated , tyrosine kinase dependent Ras activation involves the simultaneous interaction of phosphorylated Shc with the TCR zeta chain and with a second adapter protein , Grb 2 . ^^^ |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| Taken together , these results indicate that anti CD 3 induces Grb 2 hSos1 PLC gamma 1 p36 / p38 ZAP 70 complexes , which localize in the vicinity of TCR zeta . . ^^^ |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| Compared to normal thymocytes , PTP1C deficient thymocytes also showed increased constitutive tyrosine phosphorylation of the TCR complex and enhanced and prolonged TCR induced tyrosine phosphorylation of the TCR zeta and CD 3 epsilon , as well as a number of cytosolic proteins , most notably a 38 kD phosphoprotein found to associate with the Grb 2 adaptor SH 2 domain in activated thymocytes . ^^^ |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| The molecular mechanisms regulating recruitment of intracellular signaling proteins like growth factor receptor bound protein 2 ( Grb 2 ) , phospholipase Cgamma 1 , or phosphatidylinositol 3 kinase ( PI 3 kinase ) to the plasma membrane after stimulation of the T cell receptor ( TCR ) CD 3 zeta complex are not very well understood . ^^^ |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P20963 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|