| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :1.2601569 |
| In contrast , Grb 2 associated efficiently with the activated erythropoietin receptor and a significant part of Grb 2 was associated to a particulate subcellular fraction upon erythropoietin stimulation . . 1.2601569^^^ |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| We have recently shown that the SH 2 containing tyrosine phosphatase , Syp , binds directly to both the tyrosine phosphorylated form of the Epo receptor ( EpoR ) and to Grb 2 after Epo stimulation of M07e cells engineered to express high levels of human EpoRs ( T . ^^^ |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| Combined stimulation with Epo also resulted in impaired cooperation between Src defective Kit mutant and Epo R and , to a lesser extent , with Kit mutants defective in the activation of phosphatidylinositol 3 kinase or Grb 2 . ^^^ |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| However , protein interactions with the erythropoietin receptor and Grb 2 were restricted in the mutant cells . ^^^ |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| In an interleukin ( IL ) 3 dependent cell line expressing the transfected wild type EpoR , Epo , or IL 3 induced tyrosine phosphorylation of Shc and its association with Grb 2 . ^^^ These results suggest that the carboxyl terminal region of EpoR may play a crucial role in activation of MAP kinases through the Ras signaling pathway which may be activated by tyrosine phosphorylation of Shc and its association with Grb 2 . ^^^ |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| Although this mutation may destroy a consensus binding site for Grb 2 , no obvious differences either in the pattern of Epo induced tyrosine phosphorylated proteins or in the binding of Grb 2 to the Epo R were observed . ^^^ |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P19235 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|