| Interacting proteins: P15391 and P62993 |
Pubmed |
SVM Score :0.0 |
| Strikingly , the assembly of Grb 2 complexes that may couple the BCR to p 21 ( ras ) was clearly altered by the CD 19 bispecific antibody . ^^^ In addition to the reported Shc and 145 kDa phosphoproteins , a prominent 90 95 kDa phosphoprotein resembling CD 19 was detected in the Grb 2 complexes . ^^^ |
|
| Interacting proteins: P15391 and P62993 |
Pubmed |
SVM Score :0.0 |
| Systematic analysis of the role of CD 19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells : clustering of phospholipase C and Vav and of Grb 2 and Sos with different CD 19 tyrosines . ^^^ In mapping studies with altered constructs , CD 19 Y330 and / or Y 360 were necessary for binding Grb 2 and Sos . ^^^ |
|
| Interacting proteins: P15391 and P62993 |
Pubmed |
SVM Score :0.0 |
| Phosphorylated CD 19 recruits other effector molecules including Vav , Grb 2 , phosphoinositide 3 kinase , phospholipase Cgamma 2 , and c Abl , which may contribute to CD 19 regulation of B cell function . ^^^ |
|
| Interacting proteins: P15391 and P62993 |
Pubmed |
SVM Score :0.0 |
| CD 19 immunoprecipitates contain a complex of cytoplasmic proteins , including Lyn , Vav , phospholipase Cgamma 2 ( PLCgamma 2 ) , Grb 2 , and the p 85 subunit of phosphatidylinositol 3 kinase . ^^^ The affinities of binding of the SH 2 domains of Vav , p 85 , and Grb 2 to CD 19 are each in the nanomolar range by surface plasmon resonance ( Biacore ) analysis . ^^^ |
|
| Interacting proteins: P15391 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P15391 and P62993 |
Pubmed |
SVM Score :0.0 |
| NA |
|