| Meltrin alpha cytoplasmic domain interacts with SH 3 domains of Src and Grb 2 and is phosphorylated by 5 Src . ^^^ Src and Grb 2 in bovine brain extracts also bound to meltrin alpha cytoplasmic domain on affinity resin . ^^^ Furthermore , immunoprecipitation with a monoclonal antibody to meltrin alpha resulted in coprecipitation of Src and Grb 2 with meltrin alpha in cell extracts , suggesting that Src and Grb 2 are associated in vivo with meltrin alpha cytoplasmic domain . ^^^ |