| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.7342804 |
| Rab 1 interaction with a GM 130 effector complex regulates COPII vesicle cis Golgi tethering . 0.7342804^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| The GTP form of rab 1 regulates ER to Golgi transport by interaction with the vesicle tethering factor p 115 and the cis Golgi matrix protein GM 130 , also part of a complex with GRASP 65 important for the organization of cis Golgi cisternae . ^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| Recently , GM 130 , p 115 , and Golgin 84 were identified as effectors of the active conformation of rab 1 . ^^^ Cell fractionation revealed that in contrast to the mainly membrane associated rab 1 effector GM 130 , MICAL 1 displays a predominantly cytosolic localization . ^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| The accumulated receptors were colocalized with calregulin ( an ER marker ) and GM 130 ( a Golgi marker ) , consistent with Rab 1 function in regulating protein transport from the ER to the Golgi . ^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| Interestingly , we also show that Iporin interacts with another rab 1 interacting partner , the GM 130 protein . ^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| At the cis side of the Golgi , the Rab 1 GTPase binds directly to each of three coiled coil proteins : p 115 , GM 130 , and as now shown , Giantin . ^^^ Furthermore , GM 130 and Giantin bind to the acidic domain of p 115 and stimulate p 115 binding to Rab 1 , suggesting that p 115 binding to Rab 1 is regulated . ^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| Exclusion of Rab 1 effectors p 115 and GM 130 from the neurites further indicated that the centrifugal , Rab 1 mediated pathway has functions that are not directly related to ER to Golgi trafficking . ^^^ |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q08379 and P62820 |
Pubmed |
SVM Score :0.0 |
| NA |
|