| Interacting proteins: Q12967 and P62070 |
Pubmed |
SVM Score :0.86017969 |
| The interaction between RalGDS to TC 21 is direct and appears to be mediated by the effector domain of TC 21 and the carboxy terminal region of RalGDS . 0.86017969^^^ Moreover , RalGDS only binds to TC 21 in its active , GTP loaded configuration . 0.79291885^^^ |
|
| Interacting proteins: Q12967 and P62070 |
Pubmed |
SVM Score :0.0 |
| In this study , we determined that TC 21 interacts strongly with some ( RalGDS , RGL , RGL2 / Rlf , AF 6 , and the phosphatidylinositol 3 kinase ( PI3K ) catalytic subunit p110delta ) , and weakly with other Ras small middle dotGTP binding proteins . ^^^ We then examined if RalGDS , a RalA guanine nucleotide exchange factor , or PI3K are effectors for TC 21 mediated signaling and cell proliferation in murine fibroblasts . ^^^ We found that overexpression of full length RalGDS reduced the focus forming activity of activated TC 21 . ^^^ |
|
| Interacting proteins: Q12967 and P62070 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12967 and P62070 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12967 and P62070 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12967 and P62070 |
Pubmed |
SVM Score :0.0 |
| NA |
|