| MAGI 2 [ also known as S SCAM ( synaptic scaffolding molecule ) ] is a multi PDZ domain scaffolding protein that interacts with several different ligands in brain , including PTEN ( phosphatase and tensin homolog ) , dasm 1 ( dendrite arborization and synapse maturation 1 ) , dendrin , axin , beta and delta catenin , neuroligin , hyperpolarization activated cation channels , beta 1 adrenergic receptors , and NMDA receptors . ^^^ |