| Interacting proteins: Q9Y261 and P56915 |
Pubmed |
SVM Score :0.0 |
| Finally , Foxa 2 not only binds Engrailed but also Lim 1 , Gsc and Hoxa 5 homeoproteins and in the four cases Foxa 2 binds at least the homeodomain . ^^^ |
|
| Interacting proteins: Q9Y261 and P56915 |
Pubmed |
SVM Score :0.0 |
| Genes normally transcribed in organizer derived tissues , such as Gsc and Foxa 2 , are also expressed in Nodal / epiblast . ^^^ |
|
| Interacting proteins: Q9Y261 and P56915 |
Pubmed |
SVM Score :0.0 |
| The homeobox gene goosecoid ( gsc ) and the winged helix gene Hepatic Nuclear Factor 3beta ( HNF 3beta ) are co expressed in all three germ layers in the anterior primitive streak and at the rostral end of mouse embryos during gastrulation . ^^^ In this paper , we have tested the possibility of functional synergism or redundancy between these two genes during embryogenesis by generating double mutant mice for gsc and HNF 3beta . ^^^ Double mutant embryos of genotype gsc ( / ) ; HNF 3beta ( + / ) show a new phenotype as early as embryonic days 8 . 75 . ^^^ These results indicate that gsc and HNF 3beta interact to regulate Shh expression and consequently dorsal ventral patterning in the neural tube . ^^^ Our results also suggest that interaction between gsc and HNF 3beta regulates other signalling molecules required for proper development of the foregut , branchial arches and heart . . ^^^ |
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| Interacting proteins: Q9Y261 and P56915 |
Pubmed |
SVM Score :0.0 |
| An organizer population has been identified in the anterior end of the primitive streak of the mid streak stage embryo , by the expression of Hnf3beta , Gsc ( lacZ ) and Chrd , and the ability of these cells to induce a second neural axis in the host embryo . ^^^ |
|
| Interacting proteins: Q9Y261 and P56915 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y261 and P56915 |
Pubmed |
SVM Score :0.0 |
| NA |
|