| Interacting proteins: P55347 and P40425 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55347 and P40425 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P55347 and P40425 |
Pubmed |
SVM Score :0.0 |
| In contrast to the composition of the FPB complex purified from COL5A2 positive cells , the FPB complex from COL5A2 negative cells contains PBX 2 and PREP 1 but lacks PBX 1 . ^^^ |
|
| Interacting proteins: P55347 and P40425 |
Pubmed |
SVM Score :0.0 |
| Overexpression of PREP 1 in F 9 teratocarcinoma cells leads to a functionally relevant increase of PBX 2 by preventing its degradation . ^^^ We show that overexpression of PREP 1 influences the level of PBX 2 protein maintaining the PREP 1 PBX balance . ^^^ Indeed PREP 1 overexpressing cells had a higher level of PBX 2 and PBX 1b proteins . ^^^ Indeed , PBX 2 level drastically decreased after 3 h of cycloheximide treatment in control but not in PREP 1 overexpressing cells and the proteasome inhibitor MG 132 prevented PBX 2 decay in control cells . ^^^ Hence , dimerization with PREP 1 appears to decrease proteasomal degradation of PBX 2 . ^^^ |
|
| Interacting proteins: P55347 and P40425 |
Pubmed |
SVM Score :0.0 |
| In Prep 1 ( i / i ) mice , the level of Pbx 2 protein was profoundly decreased , while for Pbx 3 no definitive conclusion could be reached . ^^^ |
|
| Interacting proteins: P55347 and P40425 |
Pubmed |
SVM Score :0.0 |
| Concomitantly , Prep 1 deficiency results in the overall decrease of protein levels of its related family member Meis 1 and its partners Pbx 1 and Pbx 2 . ^^^ |
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