| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Among upstream caspases , caspase 10 , a close homolog of caspase 8 , was also proteolytically activated , but caspase 9 was not . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Caspase 8 , caspase 10 and caspase 9 are believed to be the initiator caspases at the top of the caspase signaling cascade . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| The promoter genes of apoptosis were down regulated , including caspase 8 precursor , caspase 9 and caspase 10 . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| To gain insight into the caspase cascade responsible for the execution phase of GC induced apoptosis , 697 pre B leukemic cells were stably transfected with dominant negative forms of caspase 8 , caspase 9 , or caspase 10 and the caspase 8 inhibitor CrmA . ^^^ We observed that inhibition of caspase 9 or caspase 10 activity , but not caspase 8 , caused partial resistance of 697 cells to GC induced apoptosis . ^^^ These results suggest the involvement of mitogen activated protein kinases and apical caspase 9 and caspase 10 in the GC induced apoptosis of pre B lymphocytes . . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Immunopositivity was observed for caspase 3 in 57 ( 95 % ) , caspase 8 in 56 ( 93 % ) , caspase 9 in 54 ( 90 % ) , and caspase 10 in 58 ( 97 % ) of the 60 cancers . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Furthermore , a caspase 1 inhibitor ( Z YVAD FMK ) , but not others such as Z IETD FMK ( caspase 8 inhibitor ) , Z LEHD FMK ( caspase 9 inhibitor ) , and Z AEVD FMK ( caspase 10 inhibitor ) , inhibited Gal 9 induced apoptosis . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| The expressions of apoptosis inductive genes , such as DFF 40 , Caspase 3 , Caspase 8 , Caspase 9 , Caspase 10 and CRADD , were increased by 10 ray irradiation in SAS cells with wtp 53 , but not in SAS cells expressing mp 53 . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| These results strongly suggest that caspase 10 , but not caspase 8 , might be involved in the early phase of AGE induced pericyte apoptosis , in contrast to caspase 9 and 3 like enzymes involved after DAG / ceramide production . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Caspase family inhibitor ( z VAD fmk ) , caspase 9 inhibitor ( Ac AAVALPAVLLALLAPLEHD CHO ) , and caspase 3 inhibitor ( z DEVD fmk ) partially prevented diosgenin induced apoptosis , but not caspase 8 inhibitor ( z IETD fmk ) and caspase 10 inhibitor ( z AEVD fmk ) . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| However , the caspase 9 inhibitor zLEDH fmk does not block the activation of caspase 8 , Bid , caspase 10 and caspase 3 . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Using immunoblot analyses , we further demonstrate that doppel expression activates caspase 10 as well as caspase 3 , but does not activate caspase 9 . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| Cotreatment with 15d PGJ ( 2 ) and TRAIL enhanced the sequential activation of caspase 8 , caspase 10 , caspase 9 , caspase 3 , and Bid . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| These data suggest that Mch 5 is the most upstream protease that receives the activation signal from the Fas receptor to initiate the apoptotic protease cascade that leads to activation of ICE like proteases ( TX , ICE , and ICE relIII ) , Ced 3 like proteases ( CPP 32 , Mch 2 , Mch 3 , Mch 4 , and Mch 6 ) , and the ICH 1 protease . ^^^ |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92851 and P55211 |
Pubmed |
SVM Score :0.0 |
| NA |
|