Interacting proteins: Q8TAT6 and P55072 |
Pubmed |
SVM Score :0.52727733 |
In response to oxidative stress , VCP strengthened the interaction with Npl 4 and Ufd 1 , both of which are essential in endoplasmic reticulum associated protein degradation . 0.52727733^^^ |
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Interacting proteins: Q8TAT6 and P55072 |
Pubmed |
SVM Score :0.0 |
In contrast to RNAi of VCP , RNAi of Ufd 1 or Npl 4 depleting approximately 90 % of the VCP Ufd 1 Npl4 complexes does not induce unfolded protein response , indicating that the Ufd 1 Npl4 dimer is not involved in the regulation of ER function by VCP . ^^^ |
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