Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P55042 and P15531	Pubmed	SVM Score :0.0
The remainder of the serine kinases have no effect on Rad GTP binding , intrinsic GTP hydrolysis or GTP hydrolysis stimulated by the putative tumour metastasis suppressor nm 23 . ^^^
Interacting proteins: P55042 and P15531	Pubmed	SVM Score :0.0
Interaction of the Ras related protein associated with diabetes rad and the putative tumor metastasis suppressor NM 23 provides a novel mechanism of GTPase regulation . ^^^ Purification of the GTPase activating protein ( GAP ) for Rad revealed nm 23 , a putative tumor metastasis suppressor and a development gene in Drosophila . ^^^ Antibodies against nm 23 depleted Rad GAP activity from human skeletal muscle cytosol , and bacterially expressed nm 23 reconstituted the activity . ^^^ The GAP activity of nm 23 was specific for Rad , was absent with the S105N putative dominant negative mutant of Rad , and was reduced with mutations of nm 23 . ^^^ Rad by the nucleoside diphosphate ( NDP ) kinase activity of nm 23 . ^^^
Interacting proteins: P55042 and P15531	Pubmed	SVM Score :0.0
Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm 23 . ^^^ Rad is the prototypic member of a family of novel Ras related GTPases that is normally expressed in heart , skeletal muscle , and lung and that has been shown to exhibit a novel form of bi directional interaction with the nm 23 metastasis suppressor . ^^^ Moreover , coexpression of nm 23 with wild type Rad inhibited the effect of Rad on growth of these cells in culture and markedly inhibited tumor growth in vivo . ^^^ These findings suggest that Rad may act as an oncogenic protein in breast tissues and demonstrate a potential mechanism by which interaction between Rad and nm 23 may regulate growth and tumorigenicity of breast cancer . . ^^^
Interacting proteins: P55042 and P15531	Pubmed	SVM Score :0.0
Menin has no effect on the known activities of nm 23 ; that is , nucleoside diphosphate kinase , protein kinase , or GTPase activating protein for Ras related GTPase Rad . ^^^
Interacting proteins: P55042 and P15531	Pubmed	SVM Score :0.0
NA