| Interacting proteins: Q8N5V2 and P54764 |
Pubmed |
SVM Score :0.5949775 |
| The guanine nucleotide exchange factor ( GEF ) ephexin 1 interacts with EphA 4 and has been suggested to mediate the effect of EphA on the activity of Rho GTPases , key regulators of the cytoskeleton and axon guidance . 0.5949775^^^ |
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| Interacting proteins: Q8N5V2 and P54764 |
Pubmed |
SVM Score :0.0 |
| Surprisingly , other functions of EphA 4 were regulated normally by EphA 4 ( EE ) , including midline axon guidance , hindlimb locomotion , in vitro growth cone collapse , and phosphorylation of ephexin 1 . ^^^ |
|
| Interacting proteins: Q8N5V2 and P54764 |
Pubmed |
SVM Score :0.0 |
| This suggests that EphA 4 , which has been demonstrated to activate ephexin in cultured neuronal cells , may also target Rho GTPase via an ephexin independent pathway . . ^^^ |
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