| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Higher levels of CCL 7 were present in cultures of IIP fibroblasts compared with non IIP fibroblasts , and CCL 5 , a CCR 5 agonist , significantly increased the synthesis of CCL 7 by UIP fibroblasts . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| RESULT : The chemokines of CCL 11 ( eotaxin 1 ) , CCL 24 ( eotaxin 2 ) , CCL 7 ( MCP 3 ) , CCL 13 ( MCP 4 ) , RANTES ( CCL 5 ) and receptors of CCR 2 , CCR 3 , CCR 4 , CCR 5 were differential expressed on four samples , and most of the chemokines and their receptors has tendency regulation on T help 2 ( Th 2 ) lymphocytes and involved in the prodeeds such as inducement of allergic reaction , accumulation of inflammacytes and degranulation of sensitized cells . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Expression of CX3CL1 ( fractalkine ) , CCL 7 ( MCP 3 ) , and their receptors ( CX3CR1 , CCR 1 , CCR 2 , CCR 3 , and CCR 5 ) mRNA was examined in cellular components of the maternal embryonic interface by RT PCR . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| CCR 5 is most closely related to CCR2b , another chemokine receptor that responds to monocyte chemoattractant protein ( MCP ) 1 , MCP 2 , MCP 3 , and MCP 4 . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemistry for MIP 1beta , MIP 1alpha , RANTES , eotaxin , and MCP 3 ( ligands for CCR 5 and / or CCR 3 ) revealed the presence of MIP 1beta predominantly in a subpopulation of reactive astrocytes , which were more widespread in AD than control brains , and MIP 1alpha predominantly in neurons and weakly in some microglia in both AD and controls . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| CCR 5 binds multiple CC chemokines : MCP 3 acts as a natural antagonist . ^^^ Among these ligands , MCP 3 had the remarkable property of binding CCR 5 with high affinity without eliciting a functional response , MCP 3 could also inhibit the activation of CCR 5 by MIP 1beta and may therefore be considered as a natural antagonist for CCR 5 . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Similarly , the CCR2b ligands MCP 1 and MCP 3 inhibit productive infection of PBMCs by both CCR 5 and CXCR 4 dependent strains of HIV 1 , suggesting that expression of the MCP 1 chemokine may affect HIV infection via signaling through the CCR 2 receptor and subsequent desensitization of the CCR 5 and / or CXCR 4 signaling pathway . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| In a parallel manner , binding of labeled MIP 1alpha was first shown to be attenuated by unlabeled RANTES , both of which recognize CCR 1 and CCR 5 , and then separately antagonized by MCP 3 and MIP 1beta , which bind to CCR 1 and CCR 5 , respectively . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Labeled MIP 1alpha binding was also antagonized by unlabeled MCP 3 , which is also recognized by CCR 1 , and MIP 1beta , which is a ligand for CCR 5 . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| In this study we extended our previous observations and examined various lympho hematopoietic CD 34 ( + ) cells isolated from thymus ( Th ) , cord blood ( CB ) , mobilized peripheral blood ( mPB ) , and BM for the expression of beta chemokines binding to CCR 5 , i . e . , MIP 1alpha , MIP 1beta , RANTES , MCP 2 , MCP 3 , and MCP 4 , and the alpha chemokine SDF 1 ( binding to CXCR 4 ) as these chemokines may compete with the R 5 and X 4 HIV strains , respectively , for entry into cells . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| At 26 weeks postirradiation , messages encoding the chemokines BLC ( now known as Scyb 13 ) , C 10 ( now known as Scya 6 ) , IP 10 ( now known as Scyb 10 ) , MCP 1 ( now known as Scya 2 ) , MCP 3 ( now known as Scya 7 ) , MIP 1gamma ( now known as Scya 9 ) , and RANTES ( now known as Scya 5 ) and the chemokine receptors Ccr 1 , Ccr 2 , Ccr 5 and Ccr 6 were elevated in fibrosis sensitive ( C57BL / 6 ) mice . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| We investigated the effects of a number of naturally occurring chemokines ( MIP 1alpha , MIP 1beta , RANTES , MCP 2 , MCP 3 , MCP 4 ) on different processes linked to the chemokine receptor CCR 5 in recombinant CHO cells expressing the receptor at different levels . 2 . ^^^ MIP 1alpha , MIP 1beta , RANTES , MCP 2 and MCP 4 were able to stimulate increases in intracellular calcium ions via activation of CCR 5 whereas MCP 3 was without effect . 6 . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| In parallel with down regulated SP and CCR 5 mRNA expression , cDNA array assays indicated that CP 96 , 345 treatment also inhibited IL 8 gene expression , while enhancing expression of fractalkine and monocyte chemotactic protein 3 ( MCP 3 ) . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| A number of inflammatory CC chemokines , including MIP 1 alpha , MIP 1 beta , RANTES , MCP 2 , and HCC 1 [ 9 74 ] act as CCR 5 agonists , while MCP 3 is a natural antagonist of the receptor . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Furthermore , monocyte chemotactic protein 3 ( MCP 3 ) , which binds CCR 1 but not CCR 5 and the CCR 1 specific antagonist , BX 471 , markedly inhibited OCL formation stimulated with MIP 1alpha . ^^^ |
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| Interacting proteins: P80098 and P51681 |
Pubmed |
SVM Score :0.0 |
| Finally , AMD 3100 had no effect on the Ca2+ flux induced by the CC chemokines MIP 1alpha , regulated on activation normal T cell expressed and secreted ( RANTES ; also a ligand for CCR 5 ) , or monocyte chemoattractant protein 3 ( a ligand for CCR 1 and CCR2b ) , nor was it able to induce Ca2+ fluxes by itself . ^^^ |
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