| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.69536702 |
| This study shows that eotaxin also interacts with CCR 2 and CCR 5 and can , thus , affect the responses of monocytes , which express both receptors . 0.69536702^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| The most active chemokines for resting Th ( IL 10 ) , in terms of calcium mobilization and in vitro migration , were in order of potency : CCL 2 ( monocyte chemoattractant protein 1 , CCR 2 ligand ) , CCL 4 ( macrophage inflammatory protein 1beta , CCR 5 ligand ) , CCL 3 ( macrophage inflammatory protein 1alpha , CCR1 / 5 ligand ) , CCL 17 ( thymus and activation regulated chemokine , CCR 4 ligand ) , CCL 1 ( 1 309 , CCR 8 ligand ) , CXCL 12 ( stromal derived factor 1 , CXCR 4 ) , and CCL 11 ( eotaxin , CCR 3 ligand ) . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| To do this , they have characterised haplotypes comprising alleles at 11 biallelic loci in four chemokine receptor genes ( CCR 3 , CCR 2 , CCR 5 and CCRL 2 ) , which span 150 kb on chromosome 3p21 , and haplotyes of nine biallelic loci in six chemokine genes [ MCP 1 ( CCL 2 ) , Eotaxin ( CCL 11 ) , RANTES ( CCL 5 ) , MPIF 1 ( CCL 23 ) , PARC ( CCL 18 ) and MIP 1alpha ( CCL 3 ) ] on chromosome 17q11 12 . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| RESULT : The chemokines of CCL 11 ( eotaxin 1 ) , CCL 24 ( eotaxin 2 ) , CCL 7 ( MCP 3 ) , CCL 13 ( MCP 4 ) , RANTES ( CCL 5 ) and receptors of CCR 2 , CCR 3 , CCR 4 , CCR 5 were differential expressed on four samples , and most of the chemokines and their receptors has tendency regulation on T help 2 ( Th 2 ) lymphocytes and involved in the prodeeds such as inducement of allergic reaction , accumulation of inflammacytes and degranulation of sensitized cells . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| Through analysis of mononuclear cell infiltration in WT and IL 6 deficient mice during peritoneal inflammation , we now report that IL 6 selectively governs T cell infiltration by regulating chemokine secretion ( CXCL 10 , CCL 4 , CCL 5 , CCL 11 , and CCL 17 ) and chemokine receptor ( CCR 3 , CCR 4 , CCR 5 , and CXCR 3 ) expression on the CD3+ infiltrate . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| MCP 4 induced a calcium flux in HEK 293 cells transfected with the monocyte selective MCP 1 receptor ( CCR 2B ) and the eosinophil selective eotaxin receptor ( CCR 3 ) , but not in the more widely expressed CCR 1 or CCR 5 . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| The CCR 3 ligand , eotaxin , and an anti CCR 3 antibody inhibited HIV 1 infection of microglia , as did MIP 1beta , which is a CCR 5 ligand . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| Cells treated with butyric acid acquired eosinophil characteristics ; expressed mRNA for CCR 1 and CCR 3 , but not for CCR 4 or CCR 5 ; acquired specific binding sites for macrophage inflammatory protein 1alpha and eotaxin ( the selective ligands for CCR 1 and CCR 3 , respectively ) ; and exhibited specific calcium flux and chemotaxis responses to macrophage inflammatory protein 1alpha , eotaxin , and other known CCR 1 and CCR 3 agonists . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemistry for MIP 1beta , MIP 1alpha , RANTES , eotaxin , and MCP 3 ( ligands for CCR 5 and / or CCR 3 ) revealed the presence of MIP 1beta predominantly in a subpopulation of reactive astrocytes , which were more widespread in AD than control brains , and MIP 1alpha predominantly in neurons and weakly in some microglia in both AD and controls . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| The chemokines monocyte chemotactic protein ( MCP ) 3 , MCP 4 , and eotaxin acted like RANTES , whereas macrophage inflammatory protein ( MIP ) 1alpha , MIP 1beta , MCP 1 , and stromal cell derived factor 1 were inactive , suggesting a role for the eotaxin receptor , CCR 3 , and ruling out the involvement of CCR 1 , CCR 2 , CCR 5 , and CXCR 4 . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| The CC chemokines RANTES , MIP 1alpha , MIP 1beta , and Eotaxin can suppress the replication of CCR 5 and CCR 3 dependent viruses , while SDF 1 alpha / beta suppresses that of CXCR 4 dependent strains . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| Intracellular calcium levels in astrocytes were found to increase following application of RANTES , MIP 1beta ( CCR 5 agonist ) , SDF 1alpha ( CXCR 4 agonist ) , but not eotaxin ( CCR 3 agonist ) . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| Increased expression of mRNA specific for various chemokines ( eotaxin , MIP 1alpha , MIP 2 ) and chemokine receptors ( CCR 1 , CCR 2 and CCR 5 ) was observed in the lungs of nonsensitized mice challenged with the spores . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| CCR 5 is a seven transmembrane G protein coupled receptor that binds the CC chemokines including RANTES , eotaxin , MIP 1alpha and beta . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| We report that A / J mice immunized with mc TnI developed severe inflammation of the myocardium with increased expression of inflammatory chemokines RANTES ( regulated on activation normal T cell expressed and secreted ) , monocyte chemoattractant protein 1 , macrophage inflammatory protein ( MIP ) 1alpha , MIP 1beta , MIP 2 , T cell activation gene 3 , and eotaxin and chemokine receptors CCR 1 , CCR 2 , and CCR 5 . ^^^ |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51671 and P51681 |
Pubmed |
SVM Score :0.0 |
| NA |
|