| Interacting proteins: P51668 and Q9UNE7 |
Pubmed |
SVM Score :1.0217536 |
| This activity is due , in part , to inhibition of interactions between CHIP and its cognate ubiquitin conjugating enzyme , UbcH5a , which may in turn be facilitated by ATP dependent remodeling of the BAG 2 Hsc70 CHIP heterocomplex . 1.0217536^^^ |
|
| Interacting proteins: P51668 and Q9UNE7 |
Pubmed |
SVM Score :0.0 |
| CHIP mediates attachment of ubiquitin moieties to BAG 1 in conjunction with ubiquitin conjugating enzymes of the Ubc4 / 5 family . ^^^ |
|
| Interacting proteins: P51668 and Q9UNE7 |
Pubmed |
SVM Score :0.0 |
| Moreover , incubation of nNOS with a purified system containing an E 1 ubiquitin activating enzyme , an E 2 ubiquitin carrier protein conjugating enzyme ( UbcH5a ) , CHIP , glutathione S transferase tagged ubiquitin , and an ATP generating system leads to the ubiquitylation of nNOS . ^^^ |
|
| Interacting proteins: P51668 and Q9UNE7 |
Pubmed |
SVM Score :0.0 |
| CHIP is demonstrated to function as a scaffold that nucleates the formation of a multisubunit E 3 ubiquitin ligase whose reconstituted activity toward CFTR is dependent upon Hdj 2 , Hsc 70 , and the E 2 UbcH5a . ^^^ |
|
| Interacting proteins: P51668 and Q9UNE7 |
Pubmed |
SVM Score :0.0 |
| CHIP interacts functionally and physically with the stress responsive ubiquitin conjugating enzyme family UBCH 5 . ^^^ |
|
| Interacting proteins: P51668 and Q9UNE7 |
Pubmed |
SVM Score :0.0 |
| NA |
|