| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :1.4188576 |
| We show here , by the use of chimeric E2s generated between UbcH 5 and other E2s , that a region of UbcH 5 encompassing the catalytic site cysteine residue is critical for its ability to interact with E 6 AP and RSP 5 . 1.4188576^^^ |
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| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| The complex of E 6 AP and E 6 specifically interacts with p 53 and mediates ubiquitination of p 53 in concert with the E 1 ubiquitin activating enzyme and the E 2 ubiquitin conjugating enzyme UbcH 5 . ^^^ In this paper , we describe the isolation of two human E2s , designated as UbcH 6 and UbcH 7 , that in addition to UbcH 5 can interact with E 6 AP . ^^^ Although UbcH 7 does not appear to be a member of this subfamily , UbcH 7 efficiently substitutes for UbcH 5 in E 6 AP dependent ubiquitination . ^^^ |
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| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| Nedd 4 and mouse E 6 AP are both enzymatically active E3s and function with members of the UbcH 5 family of E2s . ^^^ |
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| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| Both UbcH5B and UbcH5C form thiol ester adducts with ubiquitin , and have activities similar to UbcH5A and AtUBC 8 in the conjugation of ubiquitin to target proteins in the presence of the human ubiquitin protein ligase E 6 AP . ^^^ |
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| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51668 and Q05086 |
Pubmed |
SVM Score :0.0 |
| NA |
|