| Immunocytochemical analysis revealed that Slp 2 ( or Slp 1 ) colocalized with Rab27A in the melanosomes of melanoma cells . ^^^ Slp 2 and Rab27A were distributed to the periphery of the cells ( especially at the dendritic tips ) in the wild type melanoma cells , whereas they accumulated in the perinuclear region in the melanosome transport defective cells ( S91 / Cloudman ) . ^^^ |