| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.71224226 |
| By using the GST Tob protein that contains either full length or amino terminal half of Tob , we show that the carboxyl terminal half of Tob is relevant to its interaction with p185erbB2 . 0.71224226^^^ |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| Of these genes , TOB 1 ( transducer of ERBB 2 ) was selected for further expression analysis . ^^^ |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| The human Tob protein was identified as a molecule that interacted with the ErbB 2 protein , a receptor type protein tyrosine kinase ( RPTK ) . ^^^ |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| The molecular mechanisms by which Tob suppresses cell growth and by which ErbB 2 abrogates Tob function remain to be elucidated . ^^^ RESULTS : We show that Tob is phosphorylated on serines and threonines , but not tyrosines , by a kinase ( s ) that associates with Tob in the lysates of various cells , including ErbB 2 over expressed cells . ^^^ |
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| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| Selected targets were analyzed by RT PCR , which confirmed a decrease in transforming growth factor beta 1 ( TGF beta 1 ) , and an increase in both caspase 8 precursor ( casp 8 ) and transducer of erbB 2 ( Tob ) expression in BD . ^^^ |
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| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| Tob is a recently reported novel bone morphogenetic protein ( BMP ) inhibitor , which originally was identified by West Western procedure using ErbB 2 as a probe and contains a nuclear localization signal . ^^^ |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| Tob ( transducer of erbB 2 ) is a member of antiproliferative family proteins and acts as a bone morphogenic protein inhibitor as well as a suppressor of proliferation in T cells , which have been implicated in postmenopausal bone loss . ^^^ |
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| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| The negative cell cycle regulator , Tob ( transducer of ErbB 2 ) , is a multifunctional protein involved in hippocampus dependent learning and memory . ^^^ Tob ( transducer of ErbB 2 ) is a negative cell cycle regulator with anti proliferative activity in the periphery . ^^^ |
|
| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| The negative cell cycle regulator , Tob ( transducer of ErbB 2 ) , is involved in motor skill learning . ^^^ Tob ( transducer of ErbB 2 ) is a negative cell cycle regulator with anti proliferative activity in peripheral tissues . ^^^ Yu , The negative cell cycle regulator , Tob ( Transducer of ErbB 2 ) , is a multifunctional protein involved in hippocampus dependent learning and memory , Neuroscience 131 ( 2005 ) 647 659 ) . ^^^ |
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| Interacting proteins: P50616 and P04626 |
Pubmed |
SVM Score :0.0 |
| Tob ( Transducer of ErbB 2 ) proteins possess antiproliferative properties and are known to influence BMP signaling , but their relationship to other signaling pathways and to embryonic patterning in general was unclear . ^^^ |
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