| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| In an overlay assay with SDS / PAGE resolved and nitrocellulose transferred proteins of the nuclear envelope , 35S labeled karyopherin beta bound to at least four peptide repeat containing nucleoporins Nup 358 , Nup 214 , Nup 153 , and Nup98 . . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Nonmembrane nucleoporins Nup 153 , Nup 214 , and Nup 358 that are modified by O linked N acetylglucosamine and recognized by a monoclonal antibody were phosphorylated throughout the cell cycle and hyperphosphorylated during M phase . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| It bound to several of the repeat containing nucleoporins ( Nup 358 , Nup 214 , Nup 153 , Nup 98 , and p 62 ) in overlay and solution binding assays and was competed away by karyopherin beta 1 . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| To this end , we have used quantitative solid phase binding analysis to determine the affinity of an importin beta cargo complex for Nup 358 , the Nup 62 complex , and Nup 153 , which are in the cytoplasmic , central , and nucleoplasmic regions of the NPC , respectively . ^^^ Our results indicate that the importin beta transport complex binds to nucleoporins with progressively increasing affinity as the complex moves from Nup 358 to the Nup 62 complex and to Nup 153 . ^^^ Antibody inhibition studies support the possibility that importin beta moves from Nup 358 to Nup 153 via the Nup 62 complex during import . ^^^ |
|
| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Some of these , such as Nup 358 , Nup 214 on the cytoplasmic , and Nup 153 on the nucleoplasmic side of the NPC , failed to assemble into Nup107Nup133 depleted NPCs , whereas p 62 , a Nup at the center of the NPC , was unaffected . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Stem cell derived cardiac cells distributed the nuclear transport factor Ran in the nucleus , decreased the number of spare nuclear pore complexes from the cytosolic annulate lamellae reservoir , and expressed a set of nucleoporins , NUP 214 , NUP 358 , NUP 153 , and p 62 , involved in nuclear transport . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that RanGTP production is required to dissociate nucleoporins Nup 107 , Nup 153 and Nup 358 from Importin beta , to target them to chromatin and to induce association between separate NPC subcomplexes . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Nup 358 contains a repetitive zinc finger domain with overall organization similar to a region within Nup 153 that is critical to COPI association , yet inspection of these two zinc finger domains reveals features that also clearly distinguish them . ^^^ Significantly , targeting either Nup 153 or Nup 358 for inhibition perturbs nuclear envelope breakdown , supporting a model in which these nucleoporins play nonredundant roles , perhaps contributing to COPI recruitment platforms on both the nuclear and cytoplasmic faces of the pore . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Using the p 62 N terminal segment as bait , we affinity purified nucleoporins Nup 358 , Nup 214 and Nup 153 from crude cell extracts . ^^^ Furthermore , p 62 was isolated in complex with Nup 358 , Nup 214 and Nup 153 from growing HeLa cells , indicating that the interactions Nup358 / p62 , Nup214 / p62 and p62 / Nup153 also occur in vivo . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Live fluorescence imaging reveals early recruitment of emerin , LBR , RanBP 2 , and Nup 153 to reforming functional nuclear envelopes . ^^^ Taken together , these results showed that emerin , LBR , and several NPC components ( RanBP 2 , Nup 153 , p 62 ) , but not Tpr , reconstitute around chromosomes very early in telophase prior to the recovery of nuclear import activity . . ^^^ |
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| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| Four nucleoporins , Nup 153 , RanBP 2 , Nup 214 and Tpr are cleaved by caspases during apoptosis . ^^^ |
|
| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49792 and P49790 |
Pubmed |
SVM Score :0.0 |
| NA |
|