| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 1 is a placenta growth factor 2 receptor . ^^^ |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| Expression patterns of the angiogenic placenta growth factor and its receptor neuropilin 1 were assessed in normal human melanocytes , SV40T transformed melanocytes , and melanoma cells derived from primary and metastatic lesions . ^^^ As determined by reverse transcription polymerase chain reaction all primary and metastatic melanoma cell lines tested and SV40T transformed melanocytes coexpressed two placenta growth factor splice variants ( placenta growth factor 1 and 2 ) as well as neuropilin 1 mRNA . ^^^ Although melanoma cells expressed both , neuropilin 1 and flt 1 , exogenous homodimeric placenta growth factor had no effect on melanoma cell growth . ^^^ |
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| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| Both primary and metastatic melanoma cells were found to express the mRNAs encoding for vascular endothelial growth factor and placenta growth factor receptors ( KDR , Flt 1 , neuropilin 1 , and neuropilin 2 ) , and exposure of melanoma cells to these cytokines resulted in a specific proliferative response , supporting the hypothesis of a role of these angiogenic factors in melanoma growth . ^^^ |
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| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 1 and 2 ( NP 1 / NP 2 ) are transmembrane receptors that play a role in axonal guidance by binding of class 3 semaphorins , and in angiogenesis by binding of the vascular endothelial growth factor isoform VEGF 165 and placenta growth factor ( PLGF ) . ^^^ |
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| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| Neuropilin 1 binds vascular endothelial growth factor 165 , placenta growth factor 2 , and heparin via its b1b2 domain . ^^^ To determine the VEGF ( 165 ) and placenta growth factor 2 ( PlGF 2 ) binding sites of NRP 1 , recombinant NRP 1 domains were expressed in mammalian cells as Myc tagged , soluble proteins , and used in co precipitation experiments with 125I VEGF 165 and 125I PlGF 2 . ^^^ |
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| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| The neuropilin 1 ( NRP 1 ) and neuropilin 2 ( NRP 2 ) receptors can bind the class 3 semaphorin subfamily and the heparin binding forms of vascular endothelial growth factor ( VEGF ) and placenta growth factor ( PlGF ) . ^^^ |
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| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| Additional VEGF family members such as the heparin binding form of placenta growth factor ( PlGF 2 ) and VEGF B bind to NRP 1 , and it was also shown that both PlGF 2 and VEGF C bind to NRP 2 . ^^^ |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| The aim of this work was to investigate possible differences in peripheral blood concentrations of 13 , 14 dihydro 15 keto PGF alpha ( PGFM ) and 6 keto PGF 1 alpha ( PGIM ) , between dairy cows retaining ( RP ) and not retaining ( NRP ) their placenta . ^^^ |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49763 and O14786 |
Pubmed |
SVM Score :0.0 |
| NA |
|