| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| Maternal effect mutations in four genes clk 1 , clk 2 , clk 3 , and gro 1 interact genetically to determine both the duration of development and life span . ^^^ |
|
| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| The Clk 2 and Clk 3 dual specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre mRNA splicing . ^^^ In this study , we demonstrate that the human Clk 2 and Clk 3 ( hClk 2 and 3 ) are also found within the nucleus and display dual specificity kinase activity . ^^^ |
|
| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| Two genetically distinct mechanisms of life span extension are known : a mechanism involving genes that regulate dauer formation ( age 1 , daf 2 , daf 16 , and daf 28 ) and a mechanism involving genes that affect the rate of development and behavior ( clk 1 , clk 2 , clk 3 , and gro 1 ) . ^^^ |
|
| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| In genetic crosses , yw 23 complements other known aging mutants in C . elegans genes age 1 , daf 2 , spe 26 , clk 1 , clk 2 , clk 3 , and gro 1 . ^^^ |
|
| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| A different mechanism is specified by the clock genes clk 1 , clk 2 , clk 3 and gro 1 , which regulate metabolic activity and the pace of many temporal processes including longevity . ^^^ |
|
| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| Mutation in any of the four clock genes ( clk 1 , clk 2 , clk 3 , gro 1 ) causes an average slowing down of many temporal processes , and an increase of mean life span . ^^^ |
|
| Interacting proteins: P49760 and P49761 |
Pubmed |
SVM Score :0.0 |
| Here we showed that clk / STY , as well as other members of the family ( e . g . clk 2 , clk 3 and clk 4 ) , are up regulated during HMBA induced erythroleukemia cell differentiation . mRNAs coding for the full length and the truncated forms were responsible for the overall increased expression . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| Maternal effect mutations in four genes clk 1 , clk 2 , clk 3 , and gro 1 interact genetically to determine both the duration of development and life span . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| The Clk 2 and Clk 3 dual specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre mRNA splicing . ^^^ In this study , we demonstrate that the human Clk 2 and Clk 3 ( hClk 2 and 3 ) are also found within the nucleus and display dual specificity kinase activity . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| Two genetically distinct mechanisms of life span extension are known : a mechanism involving genes that regulate dauer formation ( age 1 , daf 2 , daf 16 , and daf 28 ) and a mechanism involving genes that affect the rate of development and behavior ( clk 1 , clk 2 , clk 3 , and gro 1 ) . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| In genetic crosses , yw 23 complements other known aging mutants in C . elegans genes age 1 , daf 2 , spe 26 , clk 1 , clk 2 , clk 3 , and gro 1 . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| A different mechanism is specified by the clock genes clk 1 , clk 2 , clk 3 and gro 1 , which regulate metabolic activity and the pace of many temporal processes including longevity . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| Mutation in any of the four clock genes ( clk 1 , clk 2 , clk 3 , gro 1 ) causes an average slowing down of many temporal processes , and an increase of mean life span . ^^^ |
|
| Interacting proteins: P49761 and P49760 |
Pubmed |
SVM Score :0.0 |
| Here we showed that clk / STY , as well as other members of the family ( e . g . clk 2 , clk 3 and clk 4 ) , are up regulated during HMBA induced erythroleukemia cell differentiation . mRNAs coding for the full length and the truncated forms were responsible for the overall increased expression . ^^^ |
|