| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| CCAAT enhancer binding protein ( C / EBP ) and AML 1 ( CBF alpha 2 ) synergistically activate the macrophage colony stimulating factor receptor promoter . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| Function of PU . 1 ( Spi 1 ) , C / EBP , and AML 1 in early myelopoiesis : regulation of multiple myeloid CSF receptor promoters . ^^^ What is the effect of targeted disruption and other mutations of the C / EBP and AML 1 proteins on myeloid development and receptor expression . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| The Hoxa 9 immortalized progenitor exhibited a promyelocytic transcriptional profile , expressing PU . 1 , AML 1 , c Myb , C / EBP alpha , and C / EBP epsilon as well as their target genes , the receptors for GM CSF , G CSF , and M CSF and the primary granule proteins myeloperoxidase and neutrophil elastase . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| Analysis of the promoter region of the G CSFR gene revealed that up regulation of G CSFR expression by AML 1 MTG8 does not depend on the AML 1 binding sequence , but on the C / EBP ( CCAAT / enhancer binding protein ) binding site . ^^^ |
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| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| Genomic DNA from 381 cancers and cell lines representing leukemias , lymphomas and a variety of solid tumors were examined for mutations of genes coding for the C / EBP beta , C / EBP alpha , PU . 1 , and AML 1 transcription factors using single strand conformation polymorphism ( SSCP ) and direct DNA sequencing . ^^^ |
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| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| In addition , the binding sites for a variety of transcription factors : AML 1 alpha , SRY , Nkx 2 . 5 , LyF 1 , p 300 , GATA 1 / 2 , HNF 3 beta , c / EBP alpha / beta and USF have been localized in the promoter region of Npr 1 gene . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| Recent data indicated that gene rearrangements were not the sole gene alterations occurring in human leukemia since point mutations could also affect the function of transcription factors playing a key role in hematopoiesis such as C / EBP alpha , GATA 1 and AML 1 . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| The promoter sequence contained consensus binding sites for several known factors , and specific binding of nuclear PU . 1 , Sp 1 , Sp 3 , USF , AML 1 , and C / EBP proteins was detectable in gel shift assays . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| This region was found to contain overlapped AML 1 and C / EBP binding site motifs . ^^^ Gel mobility shift assays using the A 2058 nuclear extract and AML 1a or C / EBPalpha ( CCAAT / enhancer binding protein alpha ) recombinant protein indicated that these two transcription factors can bind to the overlapped AML 1 / C / EBP binding site motifs on the OPN regulatory sequence from 147 to 127 . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| The present study analyzed the expression of the following 13 TFs : AML 1 , CEBPA , E2A , ETS 1 , GATA 1 , GATA 2 , GATA 3 , IKAROS , IRF 1 , PAX 5 , PU 1 , TBET and TCF 1 in 7 malignant NK cell lines together with 5 malignant NKT cell lines , 5 T cell acute lymphoblastic leukemia ( ALL ) cell lines including 3 gamma / delta T cell receptor ( TCR ) type and 2 alpha / beta TCR type , and 3 B cell precursor ( BCP ) leukemia cell lines . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| Runx 1 and c Myb act in early stage hematopoietic cells to both stimulate proliferation and differentiation , whereas C / EBPalpha , and perhaps other C / EBP family members , block progression from G 1 to S and induce terminal maturation . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| Analysis was performed on six genes known to be mutated in AML ( RUNX 1 , FLT 3 , KIT , CEBPA , PTPN 11 and NRAS ) and an additional two candidate genes ( CCND 3 and FES ) in a panel of 175 primary human AML samples that included all French American British types except M 3 , and all cytogenetic risk groups . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| In 7 of 13 cases with uniparental disomy , we identified concurrent homozygous mutations at four distinct loci ( WT 1 , FLT 3 , CEBPA , and RUNX 1 ) . ^^^ |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q01196 and P49715 |
Pubmed |
SVM Score :0.0 |
| NA |
|