| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| The cAMP response element ( CRE ) 1 site within the proximal promoter region mediated the HBx induced transactivation of the PEPCK gene through C / EBP alpha and ATF 2 . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| We demonstrate that CREB will form heterodimers with ATF 1 , but not ATF 2 , Jun , Fos , or C / EBP whereas , ATF 2 will form heterodimers with Jun and Fos , but not with C / EBP or ATF 1 . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| The protein sequence deduced from the open reading frame of a human placental cDNA encoding a cAMP responsive enhancer ( CRE ) binding protein ( CREB 327 ) has structural features characteristic of several other transcriptional transactivator proteins including jun , fos , C / EBP , myc , and CRE BP 1 . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| The human CRE BP 1 clone encoded a 54 . 5 kd protein similar at its carboxy terminus to the leucine zipper motifs found in other enhancer binding proteins such as C / EBP and c jun / AP 1 . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| As predicted , co transfection of ATF 2 with C / EBPalpha results in decreased activation of transcription driven from consensus C / EBP binding sites . ^^^ Moreover , the formation of ATF 2 : C / EBPbeta heterodimers suggests that cross family dimerization with ATF 2 may be a general property for C / EBP family proteins . . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Other D N inhibitors generated in a similar manner with the dimerization domains of Fos , Jun , C / EBP , ATF 2 , or VBP did not block CREB DNA binding activity , nor did they inhibit transcriptional activation of a minimal promoter containing a single CRE in PC 12 cells . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| In addition , we show that the CHOP AARE is related to C / EBP and ATF / CRE binding sites and binds in vitro the activating transcription factor 2 ( ATF 2 ) in starved and unstarved conditions . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| In order to determine the identities of individual B ZIP proteins in various AP 1 complexes we tested the effect of dominant negative mutants to the B ZIP proteins c Fos , ATF 2 , ATF 4 and CCAAT enhancer binding protein ( C / EBP ) on the activities of the collagenase and c Jun promoters . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| The results of these molecular studies provide evidence for an important role for the p 38 MAPK pathway in the transcriptional activation of the iNOS gene in rat glial cells involving the transcription factors nuclear factor kappa B , C / EBP , and ATF 2 . . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Only six of the Drosophila B ZIP proteins contain a `` canonical ' ' hydrophobic interface like the yeast GCN 4 , and the mammalian JUN , ATF 2 , CREB , C / EBP , and PAR leucine zippers , characterized by asparagine in the second ' a ' position . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Chromatin immunoprecipitation assays show that 5 HT induces the downstream gene C / EBP by activating CREB 1 , which recruits CBP for histone acetylation , whereas FMRFa leads to CREB 1 displacement by CREB 2 and recruitment of HDAC 5 to deacetylate histones . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| The cells selectively increased phosphorylation of p 38 MAPK , upstream dual activator MAPK kinase 3 / 6 , and downstream transcription factors activating transcription factor 2 , ETS domain transcription factor 1 , and C / EBP homologous protein in a time dependent manner . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Supershift EMSAs and Western blot analysis identified specific VT inducible DNA binding proteins for AP 1 ( cJun , phospho c jun , JunB , and JunD ) , C / EBP ( C / EBPbeta ) , CREB ( CREB 1 and ATF 2 ) , and NF kappaB ( p 50 and cRel ) . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF 4 ( CREB 2 ) and C / EBP proteins . ^^^ These results suggest that several proteins within the C / EBP family including ATF 4 ( CREB 2 ) act to constrain long term synaptic changes and memory formation . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Electrophoretic mobility shift assays demonstrated that NF kappaB binding activity induced by IL 1beta or LPS was also increased in K rasAsp 12 transfected cells , along with the binding of CREB 1 , CREM 1 , ATF 1 , ATF 2 , and Jun D to a cAMP responsive element ( CRE ) like site and the binding of C / EBPbeta to a C / EBP binding consensus site . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| The effect of sodium butyrate on aromatase expression in breast tumor fibroblasts was mediated by inhibition of phosphorylation of ATF 2 , and hence , the inhibition of binding of a transcriptional complex containing phosphorylated ATF 2 , C / EBP beta and CREB binding protein ( CBP ) to promoter II / I . 3 regulatory region . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Taken together , our results suggest that increased expression of CHOP during PC depletion depends on a C / EBP ATF element in its promoter and might be mediated by binding of ATF 2 to this element . . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| C / EBPepsilon was found to associate with other C / EBP family members , including C / EBPepsilon and CHOP as well as other proteins that are known to contain a leucine zipper protein interaction motif including CREB 2 , LDOC 1 , E6TP1 , and AF 17 . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| Other bZIP proteins , including CREB 2 , activating transcription factor 2 ( ATF 2 ) , or CAAT / enhancer binding protein ( C / EBP ) have been reported to transactivate CRE containing genes or to interfere with transactivation by CREB . ^^^ Experiments involving dominant negative bZIP mutants revealed that CREB does not heterodimerize with CREB 2 , ATF 2 , c Jun or C / EBP . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| CCAAT / enhancer binding protein ( C / EBP ) basic region / leucine zipper ( bZIP ) transcription factors have been shown to form heterodimers with cAMP responsive element binding protein 2 ( CREB 2 ) , a transcription factor involved in regulating basal and Tax mediated transactivation of the human T cell leukemia virus type 1 ( HTLV 1 ) long terminal repeat ( LTR ) . ^^^ |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49715 and P15336 |
Pubmed |
SVM Score :0.0 |
| NA |
|