| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| Polymyxin B ( PXB ) and the cecropin A melittin hybrid CA ( 1 8 ) M ( 1 18 ) ( KWKLFKKIGIGAVLKVLTTGLPALIS NH 2 ) were compared for antibiotic activity on reference and multiresistant Acinetobacter baumannii strains . ^^^ Significant differences for both peptides were observed on their inner membrane interaction and inhibition by environmental factors , supporting the use of CA ( 1 8 ) M ( 1 18 ) as a potential alternative to PXB against ACINETOBACTER : . ^^^ |
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| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| We consequently detected four and three fractions with Ca ( 2+ ) / calmodulin independent Ser ( 603 ) kinase activity on the DEAE column chromatography of bovine brain homogenate and PC 12 cell lysate , respectively , two of which were purified and identified by amino acid sequence of proteolytic fragments as p 21 activated kinase ( PAK ) 1 and PAK 3 . ^^^ |
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| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| In Triton skinned phasic ileal smooth muscle , constitutively active recombinant p 21 activated kinase ( PAK 3 ) has been shown to induce Ca ( 2+ ) independent contraction , which is accompanied by phosphorylation of caldesmon and desmin ( Van Eyk JE , Arrell DK , Foster DB , Strauss JD , Heinonen TY , Furmaniak Kazmierczak E , Cote GP , and Mak AS . ^^^ In the absence of Ca ( 2+ ) ( pCa > 9 ) , constitutively active glutathione S transferase murine PAK 3 ( GST mPAK 3 ) caused force generation of Triton skinned canine tracheal smooth muscle ( TSM ) fibers to approximately 40 % of the maximal force generated by Ca ( 2+ ) at pCa 4 . 4 . ^^^ |
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| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| In a previous work , we reported differences in lethal mechanisms between polymyxin B ( PXB ) and the cecropin A melittin ( CA M ) hybrid peptide CA ( 1 8 ) M ( 1 18 ) ( KWKLFKKIGIGAVLKVLTTGLPALIS NH 2 ) on colistin susceptible strains ( J . ^^^ |
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| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49593 and Q14155 |
Pubmed |
SVM Score :0.0 |
| NA |
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