| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| Furthermore , expression of 91 kDa MEKK 1 increased DR 4 and FAS mRNA and protein levels . ^^^ |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| Moreover , DA MEKK 1 induced Fas ligand ( FasL ) cell surface and mRNA expression , as well as FasL promoter activation . ^^^ Interference with Fas / FasL interaction prevented DA MEKK 1 mediated apoptosis . ^^^ |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| Fas induced proteolytic activation and intracellular redistribution of the stress signaling kinase MEKK 1 . ^^^ Activation of both SAPK and MEKK 1 after Fas ligation is prevented by both viral and chemical caspase 3 inhibitors , which in contrast fail to block activation of SAPK by rapidly acting cell stresses . ^^^ |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| Using inducible dominant active ( DA ) JNK kinase kinase ( MEKK 1 ) expression in Jurkat cells , we map a specific MEKK 1 regulated response element to positions 338 to 316 of the Fas ligand ( FasL ) promoter . ^^^ |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| It has been reported that cross linking Abs to Fas trigger c Jun N terminal kinase ( JNK ) signaling via caspase mediated activation of MEKK 1 ( JNK kinase kinase ) , elevation of ceramide levels or by recruitment of death domain associated protein ( DAXX ) to Fas . ^^^ |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P49327 and Q13233 |
Pubmed |
SVM Score :0.0 |
| NA |
|