| Interacting proteins: P48200 and Q9BYM8 |
Pubmed |
SVM Score :0.0 |
| Here we show that the RING finger protein HOIL 1 functions as an E 3 ligase for oxidized IRP 2 , suggesting that oxidation is a specific recognition signal for ubiquitination . ^^^ |
|
| Interacting proteins: P48200 and Q9BYM8 |
Pubmed |
SVM Score :0.0 |
| We have recently identified HOIL 1 ( heme oxidized IRP 2 ubiquitin ligase 1 ) as an E 3 ligase that recognizes a protein that has been oxidized by iron . ^^^ |
|
| Interacting proteins: P48200 and Q9BYM8 |
Pubmed |
SVM Score :0.0 |
| Moreover , the HRM in IRP 2 has been suggested to play a critical role in its recognition by the HOIL 1 ubiquitin ligase . ^^^ |
|
| Interacting proteins: P48200 and Q9BYM8 |
Pubmed |
SVM Score :0.0 |
| Here , we show that haem oxidized IRP 2 ubiquitin ligase 1 ( HOIL 1 ) , another E 3 ubiquitin ligase , interacts with SOCS 6 . ^^^ |
|
| Interacting proteins: P48200 and Q9BYM8 |
Pubmed |
SVM Score :0.0 |
| Through studies analyzing iron mediated degradation of iron regulatory protein 2 ( IRP 2 ) , a central regulator of iron metabolism in mammalian cells , we have identified a RING finger protein , HOIL 1 , as an ubiquitin ligase recognizing IRP 2 through a signal created by heme mediated oxidative modification of the protein . ^^^ |
|
| Interacting proteins: Q9BYM8 and P48200 |
Pubmed |
SVM Score :0.0 |
| Here we show that the RING finger protein HOIL 1 functions as an E 3 ligase for oxidized IRP 2 , suggesting that oxidation is a specific recognition signal for ubiquitination . ^^^ |
|
| Interacting proteins: Q9BYM8 and P48200 |
Pubmed |
SVM Score :0.0 |
| We have recently identified HOIL 1 ( heme oxidized IRP 2 ubiquitin ligase 1 ) as an E 3 ligase that recognizes a protein that has been oxidized by iron . ^^^ |
|
| Interacting proteins: Q9BYM8 and P48200 |
Pubmed |
SVM Score :0.0 |
| Moreover , the HRM in IRP 2 has been suggested to play a critical role in its recognition by the HOIL 1 ubiquitin ligase . ^^^ |
|
| Interacting proteins: Q9BYM8 and P48200 |
Pubmed |
SVM Score :0.0 |
| Through studies analyzing iron mediated degradation of iron regulatory protein 2 ( IRP 2 ) , a central regulator of iron metabolism in mammalian cells , we have identified a RING finger protein , HOIL 1 , as an ubiquitin ligase recognizing IRP 2 through a signal created by heme mediated oxidative modification of the protein . ^^^ |
|
| Interacting proteins: Q9BYM8 and P48200 |
Pubmed |
SVM Score :0.0 |
| Here , we show that haem oxidized IRP 2 ubiquitin ligase 1 ( HOIL 1 ) , another E 3 ubiquitin ligase , interacts with SOCS 6 . ^^^ |
|