| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.51525494 |
| Analysis of the expression patterns of genes encoding ligands for Notch family receptors indicated that only the Dll 4 gene is expressed in a pattern consistent with that expected for a gene encoding a ligand for the Notch 1 and Notch 4 receptors in the early embryonic vasculature . 0.51525494^^^ |
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| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.54220957 |
| Results suggest that the interaction of Dll 4 with Notch 1 may provide key signals for T cell development . . 0.54220957^^^ |
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| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.95735638 |
| Delta like 4 ( Dll 4 ) , a membrane bound ligand for Notch 1 and Notch 4 , is selectively expressed in the developing endothelium and in some tumor endothelium , and it is induced by vascular endothelial growth factor ( VEGF ) A and hypoxia . 0.95735638^^^ |
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| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.0 |
| We studied expression of Notch 1 4 and its ligand Delta like 4 ( Dll 4 ) in the developing retinal vasculature . ^^^ Possible target cells for Dll 4 signalling are retinal astrocytes ( Notch 1 positive ) , arterial pericytes ( Notch 3 positive ) or arterial endothelial cells themselves ( Notch 4 positive ) . ^^^ |
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| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.0 |
| Notably , consistent with this observation , overexpression of Foxc genes in vitro induces expression of arterial markers such as Notch 1 and its ligand Delta like 4 ( Dll 4 ) , and Foxc 1 and Foxc 2 directly activate the Dll 4 promoter via a Foxc binding site . ^^^ |
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| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.0 |
| Regulation of Notch 1 and Dll 4 by vascular endothelial growth factor in arterial endothelial cells : implications for modulating arteriogenesis and angiogenesis . ^^^ We show here that vascular endothelial growth factor ( VEGF ) but not basic fibroblast growth factor can induce gene expression of Notch 1 and its ligand , Delta like 4 ( Dll 4 ) , in human arterial endothelial cells . ^^^ |
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| Interacting proteins: Q9NR61 and P46531 |
Pubmed |
SVM Score :0.0 |
| Here , we report on the expression pattern of Notch 1 4 , Jagged 1 ( Jag 1 ) , Jag 2 , Delta like 1 ( Dll 1 ) , Dll 3 , Dll 4 , Rbpsuh , Deltex 1 ( Dtx 1 ) and Dtx 2 genes during preimplantation development from unfertilized eggs until late blastocyst stage using a RT PCR strategy . ^^^ |
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