| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| Expression of Deltex 1 during mouse embryogenesis : comparison with Notch 1 , 2 and 3 expression . ^^^ Here , we report on the expression pattern of the Deltex 1 gene during mouse embryonic development and , furthermore , we compare its expression with that of the Notch 1 , 2 and 3 genes . ^^^ |
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| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| Deltex 1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch 1 . ^^^ We now demonstrate that , in contrast to Notch 1 , enforced expression of Deltex 1 in hematopoietic progenitors results in B cell development at the expense of T cell development in fetal thymic organ culture and in vivo . ^^^ Consistent with these effects , Deltex 1 antagonizes Notch 1 signaling in transcriptional reporter assays by inhibiting coactivator recruitment . ^^^ These data suggest that a balance of inductive Notch 1 signals and inhibitory signals mediated through Deltex 1 and other modulators regulate T B lineage commitment . . ^^^ |
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| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| This can be blocked by dominant negative Notch 1 , Notch 2 , and two Deltex 1 mutants lacking the RING H 2 finger motif , but not by dominant negative RBP J or Hes 1 antisense oligonucleotides . ^^^ |
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| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| Here , we report on the expression pattern of Notch 1 4 , Jagged 1 ( Jag 1 ) , Jag 2 , Delta like 1 ( Dll 1 ) , Dll 3 , Dll 4 , Rbpsuh , Deltex 1 ( Dtx 1 ) and Dtx 2 genes during preimplantation development from unfertilized eggs until late blastocyst stage using a RT PCR strategy . ^^^ |
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| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| Gene expression profiling of thymic tumors that developed in OLIG2 / LMO1 mice revealed up regulation of Notch 1 as well as Deltex 1 ( Dtx 1 ) and pre T cell antigen receptor alpha ( Ptcra ) , two genes that are considered to be downstream of Notch 1 . ^^^ |
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| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| Here we demonstrate that Notch 1 effects on radial glia gene expression are mediated by two downstream mechanisms , one that the depends on Suppressor of Hairless [ Su ( H ) ] and the other on Deltex 1 ( DTX 1 ) . ^^^ |
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| Interacting proteins: Q86Y01 and P46531 |
Pubmed |
SVM Score :0.0 |
| In mammalian tissue culture cells , overexpression of any of the four mouse deltex homologs suppressed the transcriptional activity of E 47 , a basic helix loop helix ( bHLH ) protein , in a manner similar to suppression by an activated form of human Notch 1 or human DTX 1 . ^^^ |
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