| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.77635592 |
| KyoT 2 but not KyoT 1 repressed the RBP J mediated transcriptional activation by EBNA 2 and Notch 1 by competing with them for binding to RBP J and by dislocating RBP J from DNA . 0.77635592^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.70693784 |
| We have shown that the association of RBP Jkappa with intracellular NOTCH 1 differs significantly in B and T cells . 0.70693784^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Constitutively active human Notch 1 binds to the transcription factor CBF 1 and stimulates transcription through a promoter containing a CBF 1 responsive element . ^^^ To determine whether mammalian Notch can stimulate transcription through a CBF 1 responsive element ( RE ) , we cotransfected a CBF 1 RE containing chloramphenicol acetyltransferase reporter and N 1 ( deltaEC ) , a constitutively active form of human Notch 1 lacking the extracellular domain , into DG 75 , COS 1 , HeLa , and 293T cells , which all contain endogenous CBF 1 . ^^^ N 1 ( deltaEC ) dramatically increased chloramphenicol acetyltransferase activity in these cells , indicating functional coupling of Notch 1 and CBF 1 . ^^^ To test whether CBF 1 and Notch 1 interact physically , we tagged CBF 1 with an epitope from the influenza virus hemagglutinin or with the N terminal domain of gal 4 , and transfected the tagged CBF 1 plus N 1 ( deltaEC ) into COS 1 cells . ^^^ Cell lysates were immunoprecipitated and immunoblotted with several anti Notch 1 antibodies [ to detect N 1 ( deltaEC ) ] or with antibodies to hemagglutinin or gal 4 ( to detect CBF 1 ) . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| However , we describe constitutively active forms of Notch 1 , which inhibit muscle cell differentiation but do not interact with CBF 1 or upregulate endogenous HES 1 expression . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| CBF 1 also binds to the activated form of mammalian Notch 1 , providing a linkage between EBNA 2 function and Notch signalling . ^^^ As is the case for Notch 1 , Notch 2 interacted with the minimal repression domain of CBF 1 and was targeted to CBF 1 through the intracellular , subtransmembrane domain . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| We also examined whether Notch 1 could activate C promoter binding factor ( CBF 1 ) transcription factor using C promoter binding factor luciferase constructs , and demonstrated that this signal transduction pathway is present and can be activated in postmitotic neurons . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| We developed an assay to monitor ligand induced Notch 1 proteolysis and nuclear translocation in individual cells : Treatment of full length Notch 1 enhanced green fluorescent protein transfected Chinese hamster ovary ( CHO ) cells with a soluble preclustered form of the physiologic ligand Delta leads to rapid accumulation of the C terminus of Notch 1 in the nucleus and to transcriptional activation of a C promoter binding factor 1 ( CBF 1 ) reporter construct . ^^^ Notch 1 signaling , assessed by measuring the activity of CBF 1 , a downstream transcription factor , was impaired but not abolished by the PS 1 aspartate mutations or gamma secretase inhibitors . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| To investigate the function of Notch and the signaling events activated by Notch in myeloid development , we expressed truncated forms of Notch 1 or Notch 2 proteins that either can or can not activate the core binding factor 1 ( CBF 1 ) in 32D ( clone 3 ) myeloblasts . 32D cells proliferate as blasts in the presence of the cytokines , GM CSF or IL 3 , but they initiate differentiation and undergo granulopoiesis in the presence of granulocyte CSF ( G CSF ) . 32D cells expressing constitutively active forms of Notch 1 or Notch 2 proteins that signal through the CBF 1 pathway maintained significantly higher numbers of viable cells and exhibited less cell death during G CSF induction compared with controls . ^^^ In contrast , Notch 1 constructs that either lacked sequences necessary for CBF 1 binding or that failed to localize to the nucleus had little effect . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Consistent with previous reports , we found that disruption of furin processing of Notch 1 , either by coexpression of a furin inhibitor or by mutation of furin target sequences within Notch 1 itself , perturbed ligand dependent signaling through the well characterized mediator of Notch signal transduction , CSL ( CBF 1 , Su ( H ) , and LAG 1 ) . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| We now show , using mammalian cells transfected with full length Notch 1 , that the C terminal domain of Notch 1 rapidly translocates to the nucleus upon stimulation with the physiologic ligand Delta and initiates a CBF 1 dependent signal transduction cascade . ^^^ However , Notch 1 signaling , assessed by measuring the activity of CBF 1 , a downstream gene , was reduced but not completely abolished in the presence of either aspartate mutations or gamma secretase inhibitors . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Overexpressing human APP ( APP ( 695Sw ) ) in neurons leads to a decrease in endogenous Notch 1 signal transduction , as assessed by a CBF 1 luciferase transcription assay , by Notch C terminal domain nuclear translocation in vitro and by analysis of Notch C terminal domain generation and Notch 1 staining in vivo . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Basal expression of IkappaBalpha is controlled by the mammalian transcriptional repressor RBP J ( CBF 1 ) and its activator Notch 1 . ^^^ CBF 1 induced repression of IkappaBalpha promoter activity was reversed in HSC transfected with the Notch 1 intracellular domain ( NICD ) . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth , apoptosis , and migration via a CBF 1 / RBP Jk dependent pathway . ^^^ We investigated the role of Notch 1 and 3 receptor signaling in controlling adult SMC fate in vitro by establishing that hairy enhancer of split ( hes 1 and 5 ) and related hrt ' s ( hrt 1 , 2 , and 3 ) are direct downstream target genes of Notch 1 and 3 receptors in SMC and identified an essential role for nuclear protein CBF 1 / RBP Jk in their regulation . ^^^ Constitutive expression of active Notch 1 and 3 receptors ( Notch IC ) resulted in a significant up regulation of CBF 1 / RBP Jk dependent promoter activity and Notch target gene expression concomitant with significant increases in SMC growth while concurrently inhibiting SMC apoptosis and migration . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Constitutive activation of C promoter binding factor ( CBF 1 ) , a Notch pathway effector , also increased neurosphere frequency in FGF 2 , suggesting that the effect of Notch 1 on FGF responsiveness is mediated by CBF 1 . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Transient transfection analyses in COS 7 cells further document that a CBF 1 VP16 fusion protein and the intracellular domain of Notch 1 robustly activate a promoter containing multiple copies of the rat renin CBF 1 binding site . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| We show here that a binding site for the Notch effector CBF 1 is essential for all Blbp transcription in radial glia , and that BLBP expression is significantly reduced in the forebrains of mice lacking the Notch 1 and Notch 3 receptors . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| The expression of alpha actin , calponin , myosin , and smoothelin was examined by performing immunocytochemistry , Western blot analysis , and quantitative real time PCR in hVSMCs cultured under static conditions after forced overexpression of constitutively active Notch 1 and 3 receptors , inhibition of endogenous Cp binding factor 1 ( CBF 1 ) / recombination signal sequence binding protein Jkappa ( RBP Jkappa ) signaling , and exposure to cyclic strain using a Flexercell Tension Plus unit . ^^^ Overexpression of constitutively active Notch intracellular ( IC ) receptors ( Notch 1 IC and Notch 3 IC ) resulted in a significant downregulation of alpha actin , calponin , myosin , and smoothelin expression , an effect that was significantly attenuated after inhibition of Notch mediated , CBF 1 / RBP Jkappa dependent signaling by coexpression of RPMS 1 ( Epstein Barr virus encoded gene product ) and selective knockdown of basic helix loop helix factors [ hairy enhancer of split ( HES ) gene and Hes related transcription ( Hrt ) factors Hrt 1 , Hrt 2 , and Hrt 3 ] using targeted small interfering RNA . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| The induction of Notch 1 in human BON carcinoid cells led to high levels of functional Notch 1 , as measured by CBF 1 binding studies , resulting in activation of the Notch 1 pathway . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Furthermore , in the mouse , the phenotypes of homozygous mutant Notch 1 embryos are very similar to those of homozygous mutant RBP J kappa embryos . ^^^ RESULTS : We searched for proteins that interact with mouse RBP J kappa using the yeast two hybrid system , and in this way identified a short intracellular region ( mRAM 23 ) of the mouse Notch 1 protein that lacks any known sequence motif . ^^^ In vitro interaction studies , using proteins fused to glutathione S transferase , showed that RBP J kappa and Su ( H ) bind directly to the RAM 23 regions of mouse Notch 1 and Drosophila Notch , respectively . ^^^ Immunoprecipitation analysis showed that RBP J kappa and the mRAM 23 region of mouse Notch 1 also interact in vivo . ^^^ Further studies , including site directed mutagenesis experiments , narrowed down the region of mouse Notch 1 that interacts with RBP J kappa . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Involvement of RBP J in biological functions of mouse Notch 1 and its derivatives . ^^^ The intracellular region ( RAMIC ) of Notch 1 transactivates genes by interaction with a DNA binding protein RBP J . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Both Epstein Barr viral nuclear antigen 2 ( EBNA 2 ) and activated Notch 1 transactivate genes by interacting with the cellular protein RBP J kappa . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| The intracellular region ( RAMIC ) of the mouse Notch 1 receptor interacts with RBP J / CBF 1 , which binds to the DNA sequence CGTGGGAA and suppresses differentiation by transcriptional activation of genes regulated by RBP J . ^^^ We found that EBNA 2 and the Notch 1 RAMIC compete for binding to RBP J , indicating that their interaction sites on RBP J overlap at least partially . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| The RAM domain and ankyrin ( ANK ) repeats of mouse Notch 1 RAMIC were shown to be responsible for RBP J binding and necessary for transactivation . ^^^ Unexpectedly , the RBP J chimeric protein with the Notch 1 TAD failed to activate transcription but the activity was recovered by addition of either the RAM domain or ANK repeats . ^^^ The results suggest that the activity of Notch 1 TAD is repressed by fusion with RBP J because of the presence of a RBP J associated co repressor ( s ) , which could be displaced by either the RAM domain or ANK repeats . ^^^ Taken together , mouse Notch 1 RAMIC can experimentally be separated into three functional domains : the RAM domain and ANK repeats for RBP J binding and co repressor displacement and the C terminal TAD . . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Here we show that mouse Notch 1 RAMIC interacts with two conserved HATs , mouse PCAF and GCN 5 , and recruits each of the HATs to RBP J . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| After ligand binding , a proteolytic cleavage step occurs and the intracellular part of Notch 1 , Notch 1 IC , translocates into the nucleus , where it targets the DNA binding protein RBP J kappa / CBF1 . ^^^ The Notch 1 IC / RBP J kappa complex overcomes repression and activates the transcription of Notch target genes . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| This can be blocked by dominant negative Notch 1 , Notch 2 , and two Deltex 1 mutants lacking the RING H 2 finger motif , but not by dominant negative RBP J or Hes 1 antisense oligonucleotides . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Overexpression of constitutively active Sox 2 in neural progenitors resulted in upregulation of Notch 1 , recombination signal sequence binding protein J ( RBP J ) and hairy enhancer of split 5 ( Hes 5 ) transcripts and the Sox 2 high mobility group ( HMG ) domain seemed sufficient to confer these effects . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| In the mouse , targeted mutation of the Notch pathway genes Notch 1 and RBP Jk has demonstrated a role for these genes in somite segmentation , but a function in neurogenesis and in cell fate decisions has not been shown . ^^^ The RBP Jk mutation has stronger effects on expression of these genes than does the Notch 1 mutation , consistent with functional redundancy of Notch genes in neurogenesis . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Oncogenic forms of NOTCH 1 lacking either the primary binding site for RBP Jkappa or nuclear localization sequences retain the ability to associate with RBP Jkappa and activate transcription . ^^^ Unlike full sized NOTCH 1 , two such truncated forms of the protein either lacking a major portion of the extracellular domain ( DeltaE ) or consisting only of the intracellular domain ( ICN ) were found to activate transcription in cultured cells , presumably through RBP Jkappa response elements within DNA . ^^^ Transcriptional activation required the presence of a weak RBP Jkappa binding site within the NOTCH 1 ankyrin repeat region of the intracellular domain . ^^^ These data are most consistent with NOTCH 1 oncogenesis and transcriptional activation being independent of association with RBP Jkappa at promoter sites . . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NF kappaB 2 is a putative target gene of activated Notch 1 via RBP Jkappa . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| First , Notch 3 IC competes with Notch 1 IC for access to RBP Jk and does not activate transcription when positioned close to a promoter . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Similarly , another truncated form of NOTCH 1 , referred to as ICNW , which contains the tryptophan residue W ( 1767 ) within one of the RBP Jkappa interacting domains , repressed the LMP 1 promoter approximately twofold . ^^^ Further analysis of the truncated NOTCH 1 molecules on the LMP 1 promoter element , lacking the two RBP Jkappa binding sites , suggests that repression in Jurkat cells may be affected by the presence of the two RBP Jkappa binding sites . ^^^ However , in Jurkat cells , intracellular truncated forms of NOTCH 1 lacking the RBP Jkappa binding sites repress these EBV latent promoters . ^^^ Our data suggest that EBNA 2 and truncated intracellular nuclear localized forms of NOTCH 1 may be functionally similar in their interactions with RBP Jkappa ; however , these molecules may have distinctly different transcriptional partners in BJAB and Jurkat cells . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| However , Notch pathway molecules are essential for the maintenance of neural stem cells ; they are depleted in the early embryonic brains of RBP Jkappa ( / ) or Notch 1 ( / ) mice . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| This phenotype is stronger than the known amorphic phenotypes for notch 1 ( des ) or deltaD ( aei ) in zebrafish , but mimicks the knockout phenotype of RBP Jkappa gene in the mouse , which is the homologue of Su ( H ) . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| The aim of this study was to characterize by Northern blot analyses expression of HIF 1alpha , HIF 1alpha inducible genes ( GLUT 1 , VEGF , p 53 ) , p 48 , and genes involved in the Notch signaling pathway ( Notch 1 , Dll 1 , RBP Jk , HES 1 ) during cerulein induced AP in mice . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Induction of the p 21 ( WAF1 / Cip1 ) gene by Notch 1 activation in differentiating keratinocytes is associated with direct targeting of the RBP Jkappa protein to the p 21 promoter . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Here we show that signalling by a constitutively active membrane bound Notch 1 protein requires the proteolytic release of the Notch intracellular domain ( NICD ) , which interacts preferentially with CSL . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Although signaling through Notch 1 persisted in PS 1 deficient cells , we found a marked reduction in the appearance of a complex of a cleaved , intracellular Notch fragment ( NICD ) and a CSL protein , as previously reported [ 6 ] [ 10 ] . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Functionally , Delta 4 is indistinguishable from Jagged 1 in its abilities to inhibit myogenesis and to stimulate transcription through Notch 1 and the DNA binding protein CSL . . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Expression of a human sequence related to Drosophila Mam ( hMam 1 ) in mammalian cells augments induction of Hairy Enhancer of split ( HES ) promoters by Notch signaling . hMam 1 stabilizes and participates in the DNA binding complex of the intracellular domain of human Notch 1 and a CSL protein . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Although the intracellular domain of Notch 1 is phosphorylated and it associates with members of the CSL family , the relationship of these events is poorly understood . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| We demonstrate that in T cell and myoblast cell lines expression of the Nrarp gene is induced by the intracellular domain of the Notch 1 protein , and that this induction is mediated by a CBF1 / Su ( H ) / Lag 1 ( CSL ) dependent pathway . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Second , a 62 amino acid peptide derived from a NOTCH coactivator , Mastermind like 1 ( MAML 1 ) , forms a transcriptionally inert nuclear complex with NOTCH 1 and CSL and specifically inhibits the growth of both murine and human NOTCH 1 transformed T ALLs . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Interestingly , FGF exerts a negative effect on Notch by suppressing CSL ( CBF 1 / RBP Jk / KBF2 in mammals , Su ( H ) in Drosophila and Xenopus , and Lag 2 in Caenorhabditis elegans ) dependent transcription , and the ectopic expression of constitutively active forms of Notch 1 or Notch 2 abrogates FGF 1 release and the phenotypic effects of FGFR stimulation . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| TGF beta regulated transcription from the Hes 1 promoter in a Notch dependent manner , and the intracellular domain of Notch 1 ( NICD ) cooperated synergistically with Smad 3 , an intracellular transducer of TGF beta signals , to induce the activation of synthetic promoters containing multimerized CSL or Smad 3 binding sites . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| We report here the crystal structure of a Notch transcriptional activation complex containing the ankyrin domain of human Notch 1 ( ANK ) , the transcription factor CSL on cognate DNA , and a polypeptide from the coactivator Mastermind like 1 ( MAML 1 ) . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Ligand binding induces proteolytic cleavages in NOTCH 1 that release its intracellular domain ( ICN 1 ) , which translocates to the nucleus and activates target genes by forming a short lived nuclear complex with two other proteins , the DNA binding factor CSL and a Mastermind like ( MAML ) coactivator . ^^^ We show here that the mutation of the S 4 sequence leads to hypophosphorylation of ICN 1 ; increased NOTCH 1 signaling ; and the stabilization of complexes containing ICN 1 , CSL , and MAML 1 . ^^^ |
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| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| Here , we report on the expression pattern of Notch 1 4 , Jagged 1 ( Jag 1 ) , Jag 2 , Delta like 1 ( Dll 1 ) , Dll 3 , Dll 4 , Rbpsuh , Deltex 1 ( Dtx 1 ) and Dtx 2 genes during preimplantation development from unfertilized eggs until late blastocyst stage using a RT PCR strategy . ^^^ We show that Notch 1 , 2 , Jag 1 2 , Dll 3 , Rbpsuh and Dtx 2 transcripts are expressed at all stages . ^^^ |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06330 and P46531 |
Pubmed |
SVM Score :0.0 |
| NA |
|