| Interacting proteins: P43699 and Q92793 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P43699 and Q92793 |
Pubmed |
SVM Score :0.72137144 |
| TTF 1 interacted with SRC 1 and CBP in vitro . 0.72137144^^^ This suggests that cAMP mediated TTF 1 phosphorylation facilitates interaction with CBP and SRC 1 , resulting in its hyperacetylation , further enhancing TTF 1 DNA binding and transcriptional activity . . 0.64033104^^^ |
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| Interacting proteins: P43699 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Our laboratory has previously demonstrated that retinoic acid nuclear receptor , thyroid transcription factor 1 ( TTF 1 ) , and nuclear receptor coactivators such as cAMP response element binding protein ( CREB ) binding protein ( CBP ) / p300 and steroid receptor coactivator 1 ( SRC 1 ) form an enhanceosome on the 5 ' enhancer region of the human surfactant protein B gene . ^^^ |
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| Interacting proteins: P43699 and Q92793 |
Pubmed |
SVM Score :0.0 |
| TTF 1 protein synergistically stimulated the hSP B promoter with RARalpha , CBP , and nuclear receptor coactivators in H 441 cells . ^^^ These findings support a model in which RAR / retinoid 10 receptor , TTF 1 , coactivators , and CBP form a transcription activation complex in the upstream enhancer region of the hSP B gene . . ^^^ |
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| Interacting proteins: P43699 and Q92793 |
Pubmed |
SVM Score :0.0 |
| TTF 1 is acetylated by nuclear receptor coactivators including the activator of the thyroid and retinoic acid receptor , CREB binding protein , and steroid receptor coactivator 1 ( SRC 1 ) in cell transfection and immunoprecipitation studies . ^^^ |
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| Interacting proteins: P43699 and Q92793 |
Pubmed |
SVM Score :0.0 |
| Using chromatin immunoprecipitation , we observed that when type 2 cells were cultured in 20 % O ( 2 ) , cAMP and IL 1 stimulated the recruitment of TTF 1 , p 65 , CBP , and steroid receptor coactivator 1 to the TBE region of the SP A promoter and increased local acetylation of histone H 3 ; these effects were prevented by hypoxia . ^^^ |
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