| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Scaffolding adapter Grb 2 associated binder 2 requires Syk to transmit signals from FcepsilonRI . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Gab 2 can be a substrate of all the three major classes of non receptor tyrosine kinases associated with the IL 2R , but in terms of IL 2 signaling , JAK 3 but not Lck or Syk is essential for Gab 2 phosphorylation . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Cross linking of the beta ( 1 ) integrin on Ba / F3 cells induced rapid tyrosine phosphorylation of Gab 2 and its association with Syk kinase , SHP 2 phosphatase , and the p 85 subunit of phosphatidylinositol ( PI ) 3 kinase . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Overexpression of Gab 2 in rat basophilic leukemia 2H3 cell line cells inhibited the Fc epsilon RI induced tyrosine phosphorylation of the subunits of the receptor , and the phosphorylation and / or activation of Syk and mitogen activated protein kinase . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Fc epsilon RI induced signaling in the presence of constitutively active Lyn exhibited enhanced phosphorylation of the receptor subunits , Syk , LAT , Gab 2 , phospholipase C ( PLC ) gamma 1 and PLC gamma 2 , and production of phosphatidylinositol 3 , 4 , 5 trisphosphate . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Inhibition of actin polymerization followed by Thy 1 aggregation resulted in an increased tyrosine phosphorylation of Syk , phospholipase C gamma ( PLC gamma ) , Gab 2 and linker for activation of T cells ( LAT ) adapters , and some other signaling molecules . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Lyn and Syk were essential , whereas Fyn , Gab 2 , and the phosphoinositide 3 kinase Akt pathway were not critical for survival . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| FcepsilonRI mediated tyrosine phosphorylation of Syk , Gab 2 , and phospholipase C gamma 1 , and activation of c Jun N terminal kinase ( JNK ) , extracellular signal regulated kinase ( ERK ) , p 38 mitogen activated protein kinase ( MAP kinase ) , and inhibitor of nuclear factor kappaB kinase ( IKK ) , and generation of Rac 1 are unaffected in cells overexpressing the truncated Cbl b in the lipid raft . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| Consistent with this , tyrosine phosphorylation of Fc receptor gamma chain , Syk , Btk , and phospholipase Cgamma 2 by convulxin is reduced in the absence of Gab 2 . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| In this study , we report that FcepsilonRI aggregation leads to increased Fer / Fps kinase activities and that Fer phosphorylation downstream of FcepsilonRI is independent of Syk , Fyn , and Gab 2 but requires Lyn . ^^^ |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UQC2 and P43405 |
Pubmed |
SVM Score :0.0 |
| NA |
|