Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: Q99062 and P43405	Pubmed	SVM Score :0.0
We evaluated the involvement of Syk kinase , essential in mediating phagocytic signals by Fcgamma receptors , in G CSF induced phagocytosis , using murine myeloid 32D cells transfected with wild type ( WT ) human G CSF R ( hG CSF R ) or with a G CSF R mutant truncated at cytoplasmic amino acid 715 . ^^^ The G CSF R mutant lacks the immunoreceptor tyrosine based activation motif ( ITAM ) , putative binding site for Syk . ^^^ Our data provide evidence that the carboxy terminal region of G CSF R plays a role in the phagocytosis of IgG coated particles and that Syk and Hck kinase tyrosine phosphorylation is involved . . ^^^
Interacting proteins: Q99062 and P43405	Pubmed	SVM Score :0.0
Granulocyte colony stimulating factor receptor signaling involves the formation of a three component complex with Lyn and Syk protein tyrosine kinases . ^^^
Interacting proteins: Q99062 and P43405	Pubmed	SVM Score :0.0
Association of src kinase Lyn and non src kinase Syk with the granulocyte colony stimulating factor receptor ( G CSFR ) is not abrogated in neutrophils from severe congenital neutropenia patients with point mutations in the G CSFR mRNA . ^^^ In this study , we show that the Lyn and Syk kinases are associated with the G CSFR in neutrophils from SCN patients with point mutations in the cytoplasmic domain of the G CSFR mRNA . ^^^ These findings provide additional proof of the expression of normal G CSFRs in these patients , because the possible Syk binding motif is located between amino acid 727 and 747 in the G CSFR . . ^^^
Interacting proteins: Q99062 and P43405	Pubmed	SVM Score :0.0
To determine the role of specific PTK in G CSF signaling we expressed the human G CSFR in cell lines derived from DT 40 B cells , which lack either the Src related Lyn or Syk . ^^^
Interacting proteins: Q99062 and P43405	Pubmed	SVM Score :0.0
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Interacting proteins: Q99062 and P43405	Pubmed	SVM Score :0.0
NA